A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC 2.1.1.181

Accepted Name
23S rRNA (adenine(1618)-N(6))-methyltransferase.
Alternative Name(s)
rRNA large subunit methyltransferase F.
Reaction catalysed
S-adenosyl-L-methionine + adenine(1618) in 23S rRNA <=> S-adenosyl-L-homocysteine + rRNA containing N(6)-methyladenine(1618) in 23S rRNA
Comment(s)
  • The recombinant YbiN protein is able to methylate partially deproteinized 50 S ribosomal subunit, but neither the completely assembled 50 S subunits nor completely deproteinized 23 S rRNA.
  • Formerly EC 2.1.1.48.
Cross-references
PROSITEPDOC00871
BRENDA2.1.1.181
EC2PDB2.1.1.181
ExplorEnz2.1.1.181
PRIAM enzyme-specific profiles2.1.1.181
KEGG Ligand Database for Enzyme Nomenclature2.1.1.181
IUBMB Enzyme Nomenclature2.1.1.181
IntEnz2.1.1.181
MEDLINEFind literature relating to 2.1.1.181
MetaCyc2.1.1.181
UniProtKB/Swiss-Prot
A0KHV5, RLMF_AERHH;  A4SKI2, RLMF_AERS4;  Q5DYC3, RLMF_ALIF1;  
B5EVS5, RLMF_ALIFM;  C1DPF6, RLMF_AZOVD;  Q5LBA7, RLMF_BACFN;  
Q64RQ5, RLMF_BACFR;  Q89YP0, RLMF_BACTN;  A8AIX5, RLMF_CITK8;  
Q482M9, RLMF_COLP3;  A7MEZ1, RLMF_CROS8;  Q11XA9, RLMF_CYTH3;  
Q47C26, RLMF_DECAR;  Q6ANQ6, RLMF_DESPS;  A7ZJM2, RLMF_ECO24;  
B7UM03, RLMF_ECO27;  B7MGR5, RLMF_ECO45;  B7LC90, RLMF_ECO55;  
Q8X7W6, RLMF_ECO57;  B5YS99, RLMF_ECO5E;  B7NNN9, RLMF_ECO7I;  
B7MQR1, RLMF_ECO81;  B7M782, RLMF_ECO8A;  C4ZXX9, RLMF_ECOBW;  
B1X7D7, RLMF_ECODH;  A7ZY64, RLMF_ECOHS;  A1A947, RLMF_ECOK1;  
Q0TJP1, RLMF_ECOL5;  Q8FJM4, RLMF_ECOL6;  B1IXG1, RLMF_ECOLC;  
P75782, RLMF_ECOLI;  B7NAA7, RLMF_ECOLU;  B1LM99, RLMF_ECOSM;  
Q1REB8, RLMF_ECOUT;  A4W8E5, RLMF_ENT38;  B7LJV2, RLMF_ESCF3;  
A5FHX5, RLMF_FLAJ1;  A6H0G2, RLMF_FLAPJ;  A0M4S0, RLMF_GRAFK;  
B5XYT7, RLMF_KLEP3;  A6T6Q1, RLMF_KLEP7;  A6W2M9, RLMF_MARMS;  
Q1H501, RLMF_METFK;  Q6D958, RLMF_PECAS;  C6D8Y7, RLMF_PECCP;  
Q6LIW6, RLMF_PHOPR;  Q48MF3, RLMF_PSE14;  Q15VI3, RLMF_PSEA6;  
A6V0S3, RLMF_PSEA7;  B7UVS7, RLMF_PSEA8;  Q02RZ9, RLMF_PSEAB;  
Q9HXG4, RLMF_PSEAE;  Q1I5F5, RLMF_PSEE4;  Q4KHU0, RLMF_PSEF5;  
C3K6G1, RLMF_PSEFS;  Q3IBW7, RLMF_PSEHT;  A4XY67, RLMF_PSEMY;  
A5VZ65, RLMF_PSEP1;  Q3KHM8, RLMF_PSEPF;  B0KQK4, RLMF_PSEPG;  
Q88P77, RLMF_PSEPK;  B1JBB3, RLMF_PSEPW;  Q887M4, RLMF_PSESM;  
Q4ZXI1, RLMF_PSEU2;  A4VP05, RLMF_PSEU5;  Q4FVS6, RLMF_PSYA2;  
Q1QEW1, RLMF_PSYCK;  A1SSI8, RLMF_PSYIN;  A5WBC6, RLMF_PSYWF;  
Q21P11, RLMF_SACD2;  B5F0A4, RLMF_SALA4;  A9MIS5, RLMF_SALAR;  
B5FP91, RLMF_SALDC;  B5QXT1, RLMF_SALEP;  B5R792, RLMF_SALG2;  
B4TC80, RLMF_SALHS;  B4T083, RLMF_SALNS;  Q5PG24, RLMF_SALPA;  
A9MSU1, RLMF_SALPB;  B5BC01, RLMF_SALPK;  B4TQW9, RLMF_SALSV;  
Q8ZQN4, RLMF_SALTY;  A8GBT4, RLMF_SERP5;  A1SBR7, RLMF_SHEAM;  
B8E3W0, RLMF_SHEB2;  A3DAC9, RLMF_SHEB5;  A6WHK9, RLMF_SHEB8;  
A9KVB0, RLMF_SHEB9;  Q12T32, RLMF_SHEDO;  Q08A02, RLMF_SHEFN;  
B0TM80, RLMF_SHEHH;  A3QJF9, RLMF_SHELP;  Q8EKF9, RLMF_SHEON;  
A8HA69, RLMF_SHEPA;  A4Y1N1, RLMF_SHEPC;  A0KRF2, RLMF_SHESA;  
A8G1Q8, RLMF_SHESH;  Q0HP08, RLMF_SHESM;  Q0I0H7, RLMF_SHESR;  
A1RQ03, RLMF_SHESW;  B1KP42, RLMF_SHEWM;  B2TVC2, RLMF_SHIB3;  
Q323Y7, RLMF_SHIBS;  Q32I85, RLMF_SHIDS;  Q0T6F4, RLMF_SHIF8;  
Q83LU4, RLMF_SHIFL;  Q3Z3X8, RLMF_SHISS;  A5F7R5, RLMF_VIBC3;  
A7N060, RLMF_VIBCB;  Q9KRM2, RLMF_VIBCH;  C3LMU1, RLMF_VIBCM;  
Q87Q26, RLMF_VIBPA;  Q8D935, RLMF_VIBVU;  Q7MLD9, RLMF_VIBVY;  
A1JU40, RLMF_YERE8;  A7FGU1, RLMF_YERP3;  Q1C6E5, RLMF_YERPA;  
B2K7Y6, RLMF_YERPB;  Q7CJ72, RLMF_YERPE;  A9R6I2, RLMF_YERPG;  
Q1CHT7, RLMF_YERPN;  A4TM00, RLMF_YERPP;  Q669D4, RLMF_YERPS;  
B1JH95, RLMF_YERPY;  

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
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