ID   2.1.1.188
DE   23S rRNA (guanine(748)-N(1))-methyltransferase.
AN   23S rRNA m(1)G(748) methyltransferase.
AN   rRNA large subunit methyltransferase II.
AN   tylosin-resistance methyltransferase RlmA(II).
CA   guanosine(748) in 23S rRNA + S-adenosyl-L-methionine = H(+) + N(1)-
CA   methylguanosine(748) in 23S rRNA + S-adenosyl-L-homocysteine.
CC   -!- The enzyme specifically methylates guanine(748) at N(1) in 23S rRNA.
CC   -!- The methyltransferase RlmA(II) confers resistance to the macrolide
CC       antibiotic tylosin in the drug-producing strain Streptomyces fradiae.
CC   -!- Formerly EC 2.1.1.51.
DR   Q9S1M6, RLMA2_STRFR;
//