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ENZYME

ENZYME entry: EC 2.1.1.190

Accepted Name
23S rRNA (uracil(1939)-C(5))-methyltransferase
Alternative Name(s)
RNA uridine methyltransferase A
Reaction catalysed
S-adenosyl-L-methionine + uridine(1939) in 23S rRNA <=> 5-methyluridine(1939) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine
Comment(s)
  • The enzyme specifically methylates uracil(1939) at C(5) in 23S rRNA.
  • The enzyme contains an [4Fe-4S] cluster coordinated by four conserved cysteine residues.
Cross-references
BRENDA2.1.1.190
EC2PDB2.1.1.190
ExplorEnz2.1.1.190
PRIAM enzyme-specific profiles2.1.1.190
KEGG Ligand Database for Enzyme Nomenclature2.1.1.190
IUBMB Enzyme Nomenclature2.1.1.190
IntEnz2.1.1.190
MEDLINEFind literature relating to 2.1.1.190
MetaCyc2.1.1.190
Rhea expert-curated reactions2.1.1.190
UniProtKB/Swiss-Prot
O31503, RLMCD_BACSUQ6F847, RLMD_ACIADB7H018, RLMD_ACIB3
B7I675, RLMD_ACIB5B2HTF7, RLMD_ACIBCB0VKL3, RLMD_ACIBS
B0V5N2, RLMD_ACIBYB7J921, RLMD_ACIF2B5EPA4, RLMD_ACIF5
A1W8J9, RLMD_ACISJA0KGG9, RLMD_AERHHA4SRC5, RLMD_AERS4
Q21UR3, RLMD_ALBFTQ0VP26, RLMD_ALCBSQ5E320, RLMD_ALIF1
B5FAG4, RLMD_ALIFMB6EKM3, RLMD_ALISLQ0A8Y4, RLMD_ALKEH
F2GA29, RLMD_ALTMDF5ZEI8, RLMD_ALTNAQ5P841, RLMD_AROAE
A1K4G2, RLMD_AZOSBQ2L016, RLMD_BORA1Q7WI42, RLMD_BORBR
Q7W676, RLMD_BORPAQ7VXM6, RLMD_BORPEA0K7U1, RLMD_BURCH
Q0BEW2, RLMD_BURCMQ39FQ4, RLMD_BURL3Q62JV9, RLMD_BURMA
Q1BGX9, RLMD_BURO1Q3JRP8, RLMD_BURP1Q63UT8, RLMD_BURPS
Q2SWE9, RLMD_BURTAB3PL62, RLMD_CELJUQ1QX18, RLMD_CHRSD
Q7NWP9, RLMD_CHRVOA8ANZ1, RLMD_CITK8Q47WQ1, RLMD_COLP3
A7MQZ8, RLMD_CROS8Q1LLI5, RLMD_CUPMCQ0K956, RLMD_CUPNH
Q46ZH7, RLMD_CUPPJQ47HS4, RLMD_DECARA5EXR9, RLMD_DICNV
Q8XED8, RLMD_ECO57A1AEX2, RLMD_ECOK1Q0TE74, RLMD_ECOL5
Q8FEG6, RLMD_ECOL6P55135, RLMD_ECOLIQ1R7Q7, RLMD_ECOUT
C5B8X6, RLMD_EDWI9A4WDX1, RLMD_ENT38B2VFZ2, RLMD_ERWT9
E1SSZ4, RLMD_FERBDQ14IC3, RLMD_FRAT1Q2A275, RLMD_FRATH
A0Q5J5, RLMD_FRATNQ0BKU7, RLMD_FRATOQ5NGX1, RLMD_FRATT
Q7VKU9, RLMD_HAEDUQ4QNK7, RLMD_HAEI8P44643, RLMD_HAEIN
E1W218, RLMD_HAEP3Q2SL27, RLMD_HAHCHE1V4F9, RLMD_HALED
Q0I127, RLMD_HISS1Q31DJ1, RLMD_HYDCUQ5R111, RLMD_IDILO
B5XV15, RLMD_KLEP3A6TD57, RLMD_KLEP7Q5X5A8, RLMD_LEGPA
A5IBU7, RLMD_LEGPCQ5ZVI4, RLMD_LEGPHQ5WW81, RLMD_LEGPL
Q65W13, RLMD_MANSMF2JTX5, RLMD_MARM1A6VUQ2, RLMD_MARMS
A1U2U9, RLMD_MARN8F6CY50, RLMD_MARPPQ606W5, RLMD_METCA
Q1H069, RLMD_METFKE4ZBM0, RLMD_NEIL0Q2Y6W3, RLMD_NITMU
Q3JCY2, RLMD_NITOCA1TSE0, RLMD_PARC0Q13Z67, RLMD_PARXL
Q9CJX3, RLMD_PASMUQ6D178, RLMD_PECASC6DDJ9, RLMD_PECCP
P55136, RLMD_PHOASQ7N839, RLMD_PHOLLQ6LMS7, RLMD_PHOPR
A1VQF1, RLMD_POLNAB1XU70, RLMD_POLNSQ128S1, RLMD_POLSJ
B4EUF2, RLMD_PROMHQ48FH7, RLMD_PSE14Q02I93, RLMD_PSEAB
Q9I525, RLMD_PSEAEQ1IDL9, RLMD_PSEE4Q4K898, RLMD_PSEF5
Q3K8E9, RLMD_PSEPFQ88MB9, RLMD_PSEPKQ885Y8, RLMD_PSESM
Q3IDM6, RLMD_PSET1Q4ZQ44, RLMD_PSEU2Q4FUU5, RLMD_PSYA2
Q1QDU2, RLMD_PSYCKA1SSB8, RLMD_PSYINQ8Y035, RLMD_RALN1
B2U9U3, RLMD_RALPJQ9JP88, RLMD_RUBGIQ57KF9, RLMD_SALCH
Q5PEJ4, RLMD_SALPAQ8Z446, RLMD_SALTIQ8ZME1, RLMD_SALTY
A1S4D3, RLMD_SHEAMB8E8S1, RLMD_SHEB2A3D7B5, RLMD_SHEB5
A6WR37, RLMD_SHEB8A9KYI1, RLMD_SHEB9Q12PZ8, RLMD_SHEDO
Q086B4, RLMD_SHEFNB0TK00, RLMD_SHEHHQ8EBQ3, RLMD_SHEON
A8H1S1, RLMD_SHEPAA4Y952, RLMD_SHEPCB8CJP2, RLMD_SHEPW
A0KU76, RLMD_SHESAA8FSS4, RLMD_SHESHQ0HL77, RLMD_SHESM
Q0HXI0, RLMD_SHESRA1RHE4, RLMD_SHESWB1KPU0, RLMD_SHEWM
Q31XK5, RLMD_SHIBSQ32CD0, RLMD_SHIDSQ0T1Q1, RLMD_SHIF8
Q83QD5, RLMD_SHIFLQ3YY71, RLMD_SHISSB4SRK6, RLMD_STRM5
B2FPX2, RLMD_STRMKQ3SK67, RLMD_THIDAC4LBR5, RLMD_TOLAT
A1WME3, RLMD_VEREIA5CXB2, RLMD_VESOHB7VK72, RLMD_VIBA3
A7MTS9, RLMD_VIBC1A5F5I8, RLMD_VIBC3Q9KPC1, RLMD_VIBCH
C3LQZ5, RLMD_VIBCMQ87LP5, RLMD_VIBPAQ8DC67, RLMD_VIBVU
Q7MHP7, RLMD_VIBVYQ8PMU6, RLMD_XANACQ4USG1, RLMD_XANC8
Q8PB48, RLMD_XANCPQ3BVV1, RLMD_XANE5Q2P4L7, RLMD_XANOM
Q5H1Q8, RLMD_XANORQ9PAY7, RLMD_XYLFAQ87BR3, RLMD_XYLFT
A1JJR0, RLMD_YERE8

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
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