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ENZYME

ENZYME entry: EC 2.1.1.198

PURL: https://purl.expasy.org/enzyme/EC/2.1.1.198
Accepted Name
16S rRNA (cytidine(1402)-2'-O)-methyltransferase
Reaction catalysed
cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine + H(+)
Comment(s)
  • RsmI catalyzes the 2'-O-methylation of cytidine(1402) and RsmH (EC 2.1.1.199) catalyzes the N(4)-methylation of cytidine(1402) in 16S rRNA.
  • Both methylations are necessary for efficient translation initiation at the UUG and GUG codons.
Cross-references
BRENDA2.1.1.198
EC2PDB2.1.1.198
ExplorEnz2.1.1.198
KEGG Ligand Database for Enzyme Nomenclature2.1.1.198
IUBMB Enzyme Nomenclature2.1.1.198
MEDLINEFind literature relating to 2.1.1.198
MetaCyc2.1.1.198
Rhea expert-curated reactions2.1.1.198
UniProtKB/Swiss-Prot
P37544, RSMI_BACSUQ661J3, RSMI_BORGPP57192, RSMI_BUCAI
Q8KA29, RSMI_BUCAPQ89AY5, RSMI_BUCBPA0RMQ7, RSMI_CAMFF
B5Y7N9, RSMI_COPPDP67088, RSMI_ECO57P67087, RSMI_ECOLI
Q2NAK3, RSMI_ERYLHP45298, RSMI_HAEINQ9KGL2, RSMI_HALH5
Q9ZLS8, RSMI_HELPJP56204, RSMI_HELPYB4U6H0, RSMI_HYDS0
Q053G0, RSMI_LEPBLB0SPB4, RSMI_LEPBPC5J6H5, RSMI_MESCH
Q08329, RSMI_MICOLP0A641, RSMI_MYCBOP47302, RSMI_MYCGE
P75046, RSMI_MYCPNQ98RF5, RSMI_MYCPUP9WGW6, RSMI_MYCTO
P9WGW7, RSMI_MYCTUQ9JWJ7, RSMI_NEIMAQ9JXE3, RSMI_NEIMB
Q9CN04, RSMI_PASMUQ9HVZ3, RSMI_PSEAEQ98DM9, RSMI_RHILO
Q9ZCJ3, RSMI_RICPRQ9A186, RSMI_STRP1P0DF46, RSMI_STRP3
Q5XDL7, RSMI_STRP6Q8P2A6, RSMI_STRP8P0DF47, RSMI_STRPQ
P74038, RSMI_SYNY3Q9WZG8, RSMI_THEMAO83940, RSMI_TREPA
Q9KUD9, RSMI_VIBCHQ9PFV5, RSMI_XYLFAQ87B70, RSMI_XYLFT

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