ID   2.1.1.208
DE   23S rRNA (uridine(2479)-2'-O)-methyltransferase.
CA   uridine(2479) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-
CA   methyluridine(2479) in 23S rRNA + S-adenosyl-L-homocysteine + H(+).
CC   -!- Streptomyces viridochromogenes produces the antibiotic avilamycin A
CC       which binds to the 50S ribosomal subunit to inhibit protein
CC       synthesis.
CC   -!- To protect itself from the antibiotic, Streptomyces viridochromogenes
CC       utilizes two methyltransferases, 23S rRNA (uridine(2479)-2'-O)-
CC       methyltransferase and EC 2.1.1.209 whose actions confer avilamycin
CC       resistance to the RNA.
DR   Q9F5K6, AVRB_STRVR ;
//