Expasy logo

ENZYME

ENZYME entry: EC 2.1.1.230

Accepted Name
23S rRNA (adenosine(1067)-2'-O)-methyltransferase
Alternative Name(s)
23S rRNA A(1067) 2'-methyltransferase
nosiheptide-resistance methyltransferase
thiostrepton-resistance methylase
Reaction catalysed
adenosine(1067) in 23S rRNA + S-adenosyl-L-methionine = 2'-O-methyladenosine(1067) in 23S rRNA + H(+) + S-adenosyl-L-homocysteine
Comment(s)
  • The methylase that is responsible for autoimmunity in the thiostrepton producer Streptomyces azureus, renders ribosomes completely resistant to thiostrepton.
  • Formerly EC 2.1.1.66.
Cross-references
BRENDA2.1.1.230
EC2PDB2.1.1.230
ExplorEnz2.1.1.230
PRIAM enzyme-specific profiles2.1.1.230
KEGG Ligand Database for Enzyme Nomenclature2.1.1.230
IUBMB Enzyme Nomenclature2.1.1.230
IntEnz2.1.1.230
MEDLINEFind literature relating to 2.1.1.230
MetaCyc2.1.1.230
Rhea expert-curated reactions2.1.1.230
UniProtKB/Swiss-Prot
P52391, NSHR_STRASP18644, TSNR_STRAJP52393, TSNR_STRLU

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-