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ENZYME

ENZYME entry: EC 2.1.1.252

PURL: https://purl.expasy.org/enzyme/EC/2.1.1.252
Accepted Name
tetramethylammonium--corrinoid protein Co-methyltransferase
Alternative Name(s)
tetramethylammonium methyltransferase
Reaction catalysed
tetramethylammonium + Co(I)-[tetramethylammonium-specific corrinoid protein] + H(+) = methyl-Co(III)-[tetramethylammonium-specific corrinoid protein] + trimethylamine
Comment(s)
  • The enzyme, which catalyzes the transfer of a methyl group from tetramethylammonium to a tetramethylammonium-specific corrinoid protein (MtqC), is involved in methanogenesis from tetramethylammonium.
  • Methylation of the corrinoid protein requires the central cobalt to be in the Co(I) state.
  • During methylation the cobalt is oxidized to the Co(III) state.
  • The methylated corrinoid protein is substrate for EC 2.1.1.253.
Cross-references
BRENDA2.1.1.252
EC2PDB2.1.1.252
ExplorEnz2.1.1.252
KEGG Ligand Database for Enzyme Nomenclature2.1.1.252
IUBMB Enzyme Nomenclature2.1.1.252
MEDLINEFind literature relating to 2.1.1.252
MetaCyc2.1.1.252
Rhea expert-curated reactions2.1.1.252

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-