ENZYME entry: EC 2.1.1.292
Accepted Name |
carminomycin 4-O-methyltransferase.
|
Reaction catalysed |
carminomycin + S-adenosyl-L-methionine <=> daunorubicin + H(+) + S-adenosyl-L-homocysteine |
Comment(s) |
- The enzymes from the Gram-positive bacteria Streptomyces sp. C5 and
Streptomyces peucetius are involved in the biosynthesis of the
anthracycline daunorubicin.
- In vitro the enzyme from Streptomyces sp. C5 also catalyzes the 4-O-
methylation of 13-dihydrocarminomycin, rhodomycin D and 10-carboxy-
13-deoxycarminomycin.
|
Cross-references |
BRENDA | 2.1.1.292 |
EC2PDB | 2.1.1.292 |
ExplorEnz | 2.1.1.292 |
PRIAM enzyme-specific profiles | 2.1.1.292 |
KEGG Ligand Database for Enzyme Nomenclature | 2.1.1.292 |
IUBMB Enzyme Nomenclature | 2.1.1.292 |
IntEnz | 2.1.1.292 |
MEDLINE | Find literature relating to 2.1.1.292 |
MetaCyc | 2.1.1.292 |
Rhea expert-curated reactions | 2.1.1.292 |
UniProtKB/Swiss-Prot |
|
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