ID   2.1.1.294
DE   3-O-phospho-polymannosyl GlcNAc-diphospho-ditrans,octacis-undecaprenol
DE   3-phospho-methyltransferase.
CA   3-O-phospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-(1->3)-
CA   alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-alpha-D-Man-
CA   (1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-
CA   di-trans,octa-cis-undecaprenyl diphosphate + S-adenosyl-L-methionine =
CA   3-O-methylphospho-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-Man-
CA   (1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-(1->2)](n)-
CA   alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-GlcNAc-
CA   di-trans,octa-cis-undecaprenyl diphosphate + S-adenosyl-L-homocysteine.
CC   -!- The enzyme is involved in the biosynthesis of the polymannose
CC       O-polysaccharide in the outer leaflet of the membrane of Escherichia
CC       coli serotype O9a.
CC   -!- O-polysaccharide structures vary extensively because of differences
CC       in the number and type of sugars in the repeat unit.
CC   -!- The dual kinase/methylase WbdD also catalyzes the preceding
CC       phosphorylation of alpha-D-Man-(1->2)-alpha-D-Man-(1->2)-[alpha-D-
CC       Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->2)-alpha-D-Man-
CC       (1->2)]N-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-alpha-D-Man-(1->3)-
CC       alpha-D-GlcNAc-diphospho-ditrans,octacis-undecaprenol (cf.
CC       EC 2.7.1.181).
DR   Q47592, WBDD2_ECOLX;  J7I4B7, WBDD_ECOLX ;
//