ID 2.1.1.311 DE 25S rRNA (cytosine(2278)-C(5))-methyltransferase. CA cytidine(2278) in 25S rRNA + S-adenosyl-L-methionine = CA 5-methylcytidine(2278) in 25S rRNA + H(+) + S-adenosyl-L-homocysteine. CC -!- The enzyme, found in eukaryotes, is specific for 25S cytosine(2278). CC -!- The numbering corresponds to the enzyme from the yeast Saccharomyces CC cerevisiae. DR P53972, RCM1_YEAST ; //