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ENZYME entry: EC 2.1.1.316

Accepted Name
Mitomycin 6-O-methyltransferase.
Alternative Name(s)
Mitomycin 7-O-methyltransferase.
Reaction catalysed
  • S-adenosyl-L-methionine + 6-demethylmitomycin A <=> S-adenosyl-L-homocysteine + mitomycin A
  • S-adenosyl-L-methionine + 6-demethylmitomycin B <=> S-adenosyl-L-homocysteine + mitomycin B
Comment(s)
The enzyme, characterized from the bacterium Streptomyces lavendulae, is involved in the biosynthesis of the quinone-containing antibiotics mitomycin A and mitomycin B.
Cross-references
BRENDA2.1.1.316
EC2PDB2.1.1.316
ExplorEnz2.1.1.316
PRIAM enzyme-specific profiles2.1.1.316
KEGG Ligand Database for Enzyme Nomenclature2.1.1.316
IUBMB Enzyme Nomenclature2.1.1.316
IntEnz2.1.1.316
MEDLINEFind literature relating to 2.1.1.316
MetaCyc2.1.1.316
UniProtKB/Swiss-Prot
Q9X5T6, MMCR_STRLA

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