ID   2.1.1.319
DE   type I protein arginine methyltransferase.
CA   L-arginyl-[protein] + 2 S-adenosyl-L-methionine = 2 H(+) +
CA   N(omega),N(omega)-dimethyl-L-arginyl-[protein] + 2 S-adenosyl-L-
CA   homocysteine.
CC   -!- This eukaryotic enzyme catalyzes the sequential dimethylation of one
CC       of the terminal guanidino nitrogen atoms in arginine residues,
CC       resulting in formation of asymmetric dimethylarginine residues.
CC   -!- Some forms (e.g. PRMT1) have a very wide substrate specificity, while
CC       others (e.g. PRMT4 and PRMT6) are rather specific.
CC   -!- The enzyme has a preference for methylating arginine residues that
CC       are flanked by one or more glycine residues.
CC   -!- PRMT1 is responsible for the bulk (about 85%) of total protein
CC       arginine methylation activity in mammalian cells. cf. EC 2.1.1.320,
CC       EC 2.1.1.321 and EC 2.1.1.322.
CC   -!- Formerly EC 2.1.1.23, EC 2.1.1.124, EC 2.1.1.125 and EC 2.1.1.126.
DR   Q9MAT5, ANM10_ARATH;  A2Y953, ANM10_ORYSI;  Q9SNQ2, ANM10_ORYSJ;
DR   Q9SU94, ANM11_ARATH;  Q84W92, ANM13_ARATH;  A3KPF2, ANM14_ARATH;
DR   Q8GWT4, ANM15_ARATH;  Q8AV13, ANM1A_XENLA;  Q6VRB0, ANM1B_XENLA;
DR   Q9U2X0, ANM1_CAEEL ;  Q54EF2, ANM1_DICDI ;  Q99873, ANM1_HUMAN ;
DR   Q9JIF0, ANM1_MOUSE ;  Q63009, ANM1_RAT   ;  Q28F07, ANM1_XENTR ;
DR   Q54HI0, ANM2_DICDI ;  P55345, ANM2_HUMAN ;  Q9R144, ANM2_MOUSE ;
DR   D9IVE5, ANM2_XENLA ;  B3DLB3, ANM2_XENTR ;  O60678, ANM3_HUMAN ;
DR   Q922H1, ANM3_MOUSE ;  O70467, ANM3_RAT   ;  Q5E9L5, ANM6_BOVIN ;
DR   Q6NWG4, ANM6_DANRE ;  Q96LA8, ANM6_HUMAN ;  Q6NZB1, ANM6_MOUSE ;
DR   Q68EZ3, ANM6_XENLA ;  B0JYW5, ANM6_XENTR ;  Q5RGQ2, ANM8B_DANRE;
DR   Q9NR22, ANM8_HUMAN ;  Q6PAK3, ANM8_MOUSE ;  Q174R2, CARM1_AEDAE;
DR   Q7Q2B7, CARM1_ANOGA;  B0W3L6, CARM1_CULQU;  Q6DC04, CARM1_DANRE;
DR   B3M1E1, CARM1_DROAN;  B3P4N5, CARM1_DROER;  B4JXV2, CARM1_DROGR;
DR   Q9VH48, CARM1_DROME;  B4KA23, CARM1_DROMO;  B4GZ20, CARM1_DROPE;
DR   Q29B63, CARM1_DROPS;  B4HJC0, CARM1_DROSE;  B4QVW6, CARM1_DROSI;
DR   B4LVS8, CARM1_DROVI;  B4NKI9, CARM1_DROWI;  B4PVH6, CARM1_DROYA;
DR   Q86X55, CARM1_HUMAN;  Q9WVG6, CARM1_MOUSE;  A2YPT7, CARM1_ORYSI;
DR   Q7XI75, CARM1_ORYSJ;  Q4AE70, CARM1_RAT  ;  A0A3Q0KHE7, CARM1_SCHMA;
DR   Q5XK84, CARM1_XENLA;  Q86XA0, MET23_HUMAN;  A2AA28, MET23_MOUSE;
DR   Q5RJL2, MET23_RAT  ;  Q6DJF8, MET23_XENLA;
//