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ENZYME

ENZYME entry: EC 2.1.1.323

PURL: https://purl.expasy.org/enzyme/EC/2.1.1.323
Accepted Name
(-)-pluviatolide 4-O-methyltransferase
Reaction catalysed
(-)-pluviatolide + S-adenosyl-L-methionine = (-)-bursehernin + S-adenosyl-L-homocysteine + H(+)
Comment(s)
The enzyme, characterized from the plant Sinopodophyllum hexandrum, is involved in the biosynthetic pathway of podophyllotoxin, a non- alkaloid toxin lignan whose derivatives are important anticancer drugs.
Cross-references
Rhea expert-curated reactions2.1.1.323
ExplorEnz2.1.1.323
IUBMB Enzyme Nomenclature2.1.1.323
UniProtKB/Swiss-Prot
A0A0N9HMN6, POMT3_SINHE
BRENDA2.1.1.323
MetaCyc2.1.1.323
KEGG Ligand Database for Enzyme Nomenclature2.1.1.323
EC2PDB2.1.1.323
MEDLINEFind literature relating to 2.1.1.323

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
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