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ENZYME entry: EC 2.1.1.323

Accepted Name
(-)-pluviatolide 4-O-methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + (-)-pluviatolide <=> S-adenosyl-L-homocysteine + (-)-bursehernin
Comment(s)
The enzyme, characterized from the plant Sinopodophyllum hexandrum, is involved in the biosynthetic pathway of podophyllotoxin, a non- alkaloid toxin lignan whose derivatives are important anticancer drugs.
Cross-references
BRENDA2.1.1.323
EC2PDB2.1.1.323
ExplorEnz2.1.1.323
PRIAM enzyme-specific profiles2.1.1.323
KEGG Ligand Database for Enzyme Nomenclature2.1.1.323
IUBMB Enzyme Nomenclature2.1.1.323
IntEnz2.1.1.323
MEDLINEFind literature relating to 2.1.1.323
MetaCyc2.1.1.323

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