Expasy logo

ENZYME

ENZYME entry: EC 2.1.1.330

Accepted Name
5'-demethylyatein 5'-O-methyltransferase
Reaction catalysed
(-)-5'-demethylyatein + S-adenosyl-L-methionine <=> (-)-yatein + H(+) + S-adenosyl-L-homocysteine
Comment(s)
The enzyme, characterized from the plant Sinopodophyllum hexandrum, is involved in the biosynthetic pathway of podophyllotoxin, a non- alkaloid toxin lignan whose derivatives are important anticancer drugs.
Cross-references
BRENDA2.1.1.330
EC2PDB2.1.1.330
ExplorEnz2.1.1.330
PRIAM enzyme-specific profiles2.1.1.330
KEGG Ligand Database for Enzyme Nomenclature2.1.1.330
IUBMB Enzyme Nomenclature2.1.1.330
IntEnz2.1.1.330
MEDLINEFind literature relating to 2.1.1.330
MetaCyc2.1.1.330
Rhea expert-curated reactions2.1.1.330
UniProtKB/Swiss-Prot
A0A0N9HTA1, DOMT1_SINHE

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-