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ENZYME entry: EC 2.1.1.330

Accepted Name
5'-demethylyatein 5'-O-methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + (-)-5'-demethylyatein <=> S-adenosyl-L-homocysteine + (-)-yatein
Comment(s)
The enzyme, characterized from the plant Sinopodophyllum hexandrum, is involved in the biosynthetic pathway of podophyllotoxin, a non- alkaloid toxin lignan whose derivatives are important anticancer drugs.
Cross-references
BRENDA2.1.1.330
EC2PDB2.1.1.330
ExplorEnz2.1.1.330
PRIAM enzyme-specific profiles2.1.1.330
KEGG Ligand Database for Enzyme Nomenclature2.1.1.330
IUBMB Enzyme Nomenclature2.1.1.330
IntEnz2.1.1.330
MEDLINEFind literature relating to 2.1.1.330
MetaCyc2.1.1.330
Rhea expert-curated reactions2.1.1.330
UniProtKB/Swiss-Prot
A0A0N9HTA1, DOMT1_SINHE

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