ID 2.1.1.339 DE xanthohumol 4-O-methyltransferase. CA S-adenosyl-L-methionine + xanthohumol = 4-O-methylxanthohumol + H(+) + CA S-adenosyl-L-homocysteine. CC -!- The enzyme from hops (Humulus lupulus) has a broad substrate CC specificity. CC -!- The best substrates in vitro are resveratrol, desmethylxanthohumol, CC chalconaringenin and isoliquiritigenin. DR B0ZB56, OMT2_HUMLU ; //