ID   2.1.1.346
DE   U6 snRNA m(6)A methyltransferase.
CA   adenosine in U6 snRNA + S-adenosyl-L-methionine = H(+) + N(6)-
CA   methyladenosine in U6 snRNA + S-adenosyl-L-homocysteine.
CC   -!- This enzyme, found in vertebrates, methylates a specific adenine in a
CC       hairpin structure of snRNA.
CC   -!- The effects of the binding of the methyltransferase to its substrate
CC       is important for the regulation of the activity of an isoform of
CC       EC 2.5.1.6, that produces S-adenosyl-L-methionine.
CC   -!- The enzyme also binds (and maybe methylates) the lncRNAs XIST and
CC       MALAT1 as well as a number of pre-mRNAs at specific positions often
CC       found in the intronic regions.
DR   Q61J97, MET16_CAEBR;  Q09357, MET16_CAEEL;  Q5ZIA0, MET16_CHICK;
DR   Q6DC64, MET16_DANRE;  Q554C9, MET16_DICDI;  Q7K3B9, MET16_DROME;
DR   Q290Z2, MET16_DROPS;  Q86W50, MET16_HUMAN;  Q9CQG2, MET16_MOUSE;
DR   Q6GR37, MET16_XENLA;  O42662, MTL16_SCHPO;
//