ID 2.1.1.350 DE menaquinone C(8)-methyltransferase. CA (1) a menaquinone + reduced [flavodoxin] + 2 S-adenosyl-L-methionine = CA 5'-deoxyadenosine + an 8-methylmenaquinone + 3 H(+) + L-methionine + CA oxidized [flavodoxin] + S-adenosyl-L-homocysteine. CA (2) a 2-demethylmenaquinone + reduced [flavodoxin] + 2 S-adenosyl-L- CA methionine = 5'-deoxyadenosine + a 2-demethyl-8-methylmenaquinone + CA 3 H(+) + L-methionine + oxidized [flavodoxin] + S-adenosyl-L- CA homocysteine. CC -!- The enzyme, found in a wide range of bacteria and archaea, is a CC radical SAM (AdoMet) enzyme that utilizes two molecules of CC S-adenosyl-L-methionine, one as the methyl group donor, and one for CC the creation of a 5'-deoxyadenosine radical that drives the reaction CC forward. //