ID 2.1.1.350 DE menaquinone C(8)-methyltransferase. CA (1) reduced [flavodoxin] + a menaquinone + 2 S-adenosyl-L-methionine = CA an 8-methylmenaquinone + oxidized [flavodoxin] + 5'-deoxyadenosine + CA L-methionine + S-adenosyl-L-homocysteine + 3 H(+). CA (2) a 2-demethylmenaquinone + reduced [flavodoxin] + 2 S-adenosyl-L- CA methionine = a 2-demethyl-8-methylmenaquinone + oxidized [flavodoxin] + CA 5'-deoxyadenosine + L-methionine + S-adenosyl-L-homocysteine + 3 H(+). CC -!- The enzyme, found in a wide range of bacteria and archaea, is a CC radical SAM (AdoMet) enzyme that utilizes two molecules of CC S-adenosyl-L-methionine, one as the methyl group donor, and one for CC the creation of a 5'-deoxyadenosine radical that drives the reaction CC forward. //