ID   2.1.1.355
DE   [histone H3]-lysine(9) N-trimethyltransferase.
CA   L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-methionine = 3 H(+) +
CA   N(6),N(6),N(6)-trimethyl-L-lysyl(9)-[histone H3] + 3 S-adenosyl-L-
CA   homocysteine.
CC   -!- This entry describes several enzymes that successively methylate the
CC       L-lysine(9) residue of histone H3 (H3K9), ultimately generating a
CC       trimethylated form.
CC   -!- These modifications influence the binding of chromatin-associated
CC       proteins.
CC   -!- In general, the methylation of H3K9 leads to transcriptional
CC       repression of the affected target genes. cf. EC 2.1.1.366,
CC       EC 2.1.1.367 and EC 2.1.1.368.
DR   O60016, CLR4_SCHPO ;  Q8X225, DIM5_NEUCR ;  A0A1L7TZE5, KMT1_FUSMA ;
DR   Q13029, PRDM2_HUMAN;  Q63755, PRDM2_RAT  ;  Q6P2A1, PRDM9_DANRE;
DR   Q9NQV7, PRDM9_HUMAN;  Q96EQ9, PRDM9_MOUSE;  P0C6Y7, PRDM9_RAT  ;
DR   Q9U263, SET26_CAEEL;  Q32KD2, SETB1_DROME;  Q28Z18, SETB1_DROPS;
DR   P45975, SUV39_DROME;  Q294B9, SUV39_DROPS;  Q2NL30, SUV91_BOVIN;
DR   O43463, SUV91_HUMAN;  O54864, SUV91_MOUSE;  Q5RB81, SUV91_PONAB;
DR   Q6NRE8, SUV91_XENLA;  Q32PH7, SUV92_BOVIN;  Q5F3W5, SUV92_CHICK;
DR   Q9H5I1, SUV92_HUMAN;  Q4R3E0, SUV92_MACFA;  Q9EQQ0, SUV92_MOUSE;
DR   Q28CQ7, SUV92_XENTR;  P20659, TRX_DROME  ;  Q24742, TRX_DROVI  ;
//