ID   2.1.1.364
DE   [histone H3]-lysine(4) N-methyltransferase.
CA   L-lysyl(4)-[histone H3] + S-adenosyl-L-methionine = H(+) + N(6)-methyl-L-
CA   lysyl(4)-[histone H3] + S-adenosyl-L-homocysteine.
CC   -!- This entry describes enzymes that catalyze a single methylation of
CC       the L-lysine(4) residue of histone H3 (H3K4), generating a
CC       monomethylated form.
CC   -!- This modifications influence the binding of chromatin-associated
CC       proteins and result in gene activation or suppression.
CC   -!- Some enzymes that catalyze this reaction continue to generate a
CC       trimethylated form; these enzymes are classified under EC 2.1.1.354.
DR   Q03164, KMT2A_HUMAN;  P55200, KMT2A_MOUSE;  Q9UMN6, KMT2B_HUMAN;
DR   O08550, KMT2B_MOUSE;  Q8NEZ4, KMT2C_HUMAN;  Q8BRH4, KMT2C_MOUSE;
DR   O14686, KMT2D_HUMAN;  Q6PDK2, KMT2D_MOUSE;  A0A163UT06, SET17_CAEEL;
DR   O15047, SET1A_HUMAN;  E9PYH6, SET1A_MOUSE;  Q9UPS6, SET1B_HUMAN;
DR   Q8CFT2, SET1B_MOUSE;  Q9NVD3, SETD4_HUMAN;  P58467, SETD4_MOUSE;
DR   Q6DHG0, SETD7_DANRE;  Q7Z0G7, SETD7_HALRO;  Q8WTS6, SETD7_HUMAN;
DR   Q8VHL1, SETD7_MOUSE;  Q4QQN5, SETD7_XENTR;  Q6K431, TRX1_ORYSJ ;
//