ID 2.1.1.369 DE [histone H3]-lysine(27) N-methyltransferase. CA L-lysyl(27)-[histone H3] + S-adenosyl-L-methionine = H(+) + N(6)-methyl- CA L-lysyl(27)-[histone H3] + S-adenosyl-L-homocysteine. CC -!- This entry describes enzymes that methylate the L-lysine-27 residue CC of histone H3 only once, generating a monomethylated form. CC -!- This modification influences the binding of chromatin-associated CC proteins. CC -!- The methylation of lysine-27 leads to transcriptional repression of CC the affected target genes. cf. EC 2.1.1.356 and EC 2.1.1.371. DR Q8VZJ1, ATXR5_ARATH; B9RU15, ATXR5_RICCO; Q9FNE9, ATXR6_ARATH; DR Q93YF5, SUVH1_TOBAC; //