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ENZYME entry: EC 2.1.1.376

Accepted Name
glycine betaine--corrinoid protein Co-methyltransferase.
Alternative Name(s)
glycine betaine methyltransferase.
Reaction catalysed
Co(I)-[glycine betaine-specific corrinoid protein] + glycine betaine + H(+) <=> methyl-Co(III)-[glycine betaine-specific corrinoid protein] + N,N-dimethylglycine
Comment(s)
  • The enzyme, which catalyzes the transfer of a methyl group from glycine betaine to a glycine betaine-specific corrinoid protein (MtgC), is involved in methanogenesis from glycine betaine in some methanogenic archaea, and in glycine betaine degradation in some bacteria.
  • Unlike similar enzymes involved in methanogenesis from methylated C1 compounds, this enzyme does not contain the unusual amino acid L-pyrrolysine.
Cross-references
BRENDA2.1.1.376
EC2PDB2.1.1.376
ExplorEnz2.1.1.376
PRIAM enzyme-specific profiles2.1.1.376
KEGG Ligand Database for Enzyme Nomenclature2.1.1.376
IUBMB Enzyme Nomenclature2.1.1.376
IntEnz2.1.1.376
MEDLINEFind literature relating to 2.1.1.376
MetaCyc2.1.1.376
Rhea expert-curated reactions2.1.1.376

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-