ID 2.1.1.38 DE O-demethylpuromycin O-methyltransferase. CA O-demethylpuromycin + S-adenosyl-L-methionine = puromycin + S-adenosyl-L- CA homocysteine + H(+). CC -!- Puromycin is the antibiotic derived from N(6)-dimethyladenosine by CC replacing the 3'-hydroxy group with an amino group and acylating this CC with 4-O-methyltyrosine. DR P42712, DMPM_STRAD ; //