ENZYME entry: EC 2.1.1.388

PURL: https://purl.expasy.org/enzyme/EC/2.1.1.388

Accepted Name
proline betaine--corrinoid protein Co-methyltransferase
Reaction catalysed
Co(I)-[quaternary-amine-specific corrinoid protein] + L-proline betaine + H(+) = methyl-Co(III)-[quaternary-amine-specific corrinoid protein] + N-methyl-L-proline
Comment(s)
The enzyme, characterized from the bacterium Eubacterium limosum, is a component of a system that transfers a methyl group from L-proline betaine to tetrahydrofolate, as part of an L-proline betaine degradation pathway. The resulting 5-methyltetrahydrofolate is processed to acetyl-CoA via the Wood--Ljungdahl pathway.
Cross-references
BRENDA	2.1.1.388
EC2PDB	2.1.1.388
ExplorEnz	2.1.1.388
KEGG Ligand Database for Enzyme Nomenclature	2.1.1.388
IUBMB Enzyme Nomenclature	2.1.1.388
MEDLINE	Find literature relating to 2.1.1.388
MetaCyc	2.1.1.388
Rhea expert-curated reactions	2.1.1.388

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-