ID 2.1.1.389 DE [methyl-Co(III) quaternary-amine-specific corrinoid protein]- DE -tetrahydrofolate methyltransferase. CA methyl-Co(III)-[quaternary-amine-specific corrinoid protein] + (6S)- CA 5,6,7,8-tetrahydrofolate = Co(I)-[quaternary-amine-specific corrinoid CA protein] + (6S)-5-methyl-5,6,7,8-tetrahydrofolate + H(+). CC -!- The enzyme, characterized from the acetogenic gut bacterium CC Eubacterium limosum, participates in a pathway for the degradation of CC some quaternary amine compounds (L-proline betaine and L-carnitine). CC -!- The enzyme catalyzes the transfer of a methyl group bound to the CC cobalt cofactor of a dedicated corrinoid protein (bacterial MtqC) to CC tetrahydrofolate. CC -!- The resulting 5-methyltetrahydrofolate is processed to acetyl-CoA via CC the Wood--Ljungdahl pathway. //