ID 2.1.1.397 DE hydroxystrychnine O-methyltransferase. CA 10-hydroxystrychnine + S-adenosyl-L-methionine = beta-colubrine + CA S-adenosyl-L-homocysteine + H(+). CC -!- The enzyme, isolated from the tree Strychnos nux-vomica, participates CC in the biosynthesis of brucine. CC -!- It can methylate 10-hydroxystrychnine, and, with lower efficiency, CC 11-hydroxystrychnine and 11-demethylbrucine. DR P0DO86, OMT_STRNX ; //