ENZYME entry: EC 2.1.1.402

PURL: https://purl.expasy.org/enzyme/EC/2.1.1.402

Accepted Name
sialate 8-O-methyltransferase
Alternative Name(s)
N-acetylneuraminate 8-O-methyltransferase
Reaction catalysed
N-acetylneuraminate + S-adenosyl-L-methionine = N-acetyl-8-O-methylneuraminate + S-adenosyl-L-homocysteine + H(+)
Comment(s)
The enzyme has been isolated from gonads of the starfish Asterias rubens. It methylates N-glycolylneuraminate with equal specificity. Oligosaccharides containing N-acetyl-alpha-neuraminyl-(2->3)-beta-D- galactosyl-(1->3)-N-acetyl-D-galactosyl structures are also methylated.
Cross-references
BRENDA	2.1.1.402
EC2PDB	2.1.1.402
ExplorEnz	2.1.1.402
KEGG Ligand Database for Enzyme Nomenclature	2.1.1.402
IUBMB Enzyme Nomenclature	2.1.1.402
MEDLINE	Find literature relating to 2.1.1.402
MetaCyc	2.1.1.402
Rhea expert-curated reactions	2.1.1.402

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
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