ID 2.1.1.403 DE methylecgonone synthase. CA (+)-ecgonone + S-adenosyl-L-methionine = ecgonone methyl ester + CA S-adenosyl-L-homocysteine. CC -!- Isolated from the plant Erythroxylum novogranatense. CC -!- The enzyme, which is highly stereoselective, is involved in cocaine CC biosynthesis. CC -!- The substrate, ecgonone, is unstable, and in the absence of the CC methyltransferase decarboxylates into tropinone. DR A0A9E9KUV1, MPBMT_ERYCB; A0A9E8M4E3, MPBMT_ERYNO; //