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ENZYME entry: EC 2.1.1.46

Accepted Name
Isoflavone 4'-O-methyltransferase.
Reaction catalysed
S-adenosyl-L-methionine + a 4'-hydroxyisoflavone <=> S-adenosyl-L-homocysteine + a 4'-methoxyisoflavone
Cofactor(s)
Mg(2+).
Comment(s)
  • The enzyme catalyzes the methylation of daidzein and genistein.
  • It does not methylate naringenin, apigenin, luteolin or kaempferol.
Cross-references
BRENDA2.1.1.46
EC2PDB2.1.1.46
ExplorEnz2.1.1.46
PRIAM enzyme-specific profiles2.1.1.46
KEGG Ligand Database for Enzyme Nomenclature2.1.1.46
IUBMB Enzyme Nomenclature2.1.1.46
IntEnz2.1.1.46
MEDLINEFind literature relating to 2.1.1.46
MetaCyc2.1.1.46
Rhea expert-curated reactions2.1.1.46
UniProtKB/Swiss-Prot
Q84KK6, I4OMT_GLYEC;  Q84KK4, I4OMT_LOTJA;  Q29U70, I4OMT_MEDTR;  
O24305, M3OM1_PEA;  

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