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ENZYME entry: EC 2.1.1.47

Accepted Name
indolepyruvate C-methyltransferase.
Alternative Name(s)
indolepyruvate 3-methyltransferase.
indolepyruvate methyltransferase.
indolepyruvic acid methyltransferase.
Reaction catalysed
indole-3-pyruvate + S-adenosyl-L-methionine <=> (R)-3-(indol-3-yl)-2-oxobutanoate + H(+) + S-adenosyl-L-homocysteine
Comment(s)
The enzyme, characterized from the bacterium Streptomyces griseus, is involved in the biosynthesis of the antibacterial drug indolmycin.
Cross-references
BRENDA2.1.1.47
EC2PDB2.1.1.47
ExplorEnz2.1.1.47
PRIAM enzyme-specific profiles2.1.1.47
KEGG Ligand Database for Enzyme Nomenclature2.1.1.47
IUBMB Enzyme Nomenclature2.1.1.47
IntEnz2.1.1.47
MEDLINEFind literature relating to 2.1.1.47
MetaCyc2.1.1.47
Rhea expert-curated reactions2.1.1.47
UniProtKB/Swiss-Prot
A0A0D4BS77, IND1_STRGR

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