Expasy logo

ENZYME

ENZYME entry: EC 2.1.1.56

Accepted Name
mRNA (guanine-N(7))-methyltransferase
Alternative Name(s)
guanine-7-methyltransferase
messenger ribonucleate guanine 7-methyltransferase
messenger RNA guanine 7-methyltransferase
Reaction catalysed
a 5'-end (5'-triphosphoguanosine)-(ribonucleoside) in mRNA + S-adenosyl-L-methionine <=> a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in mRNA + S-adenosyl-L-homocysteine
Comment(s)
The terminal N(7)-methylguanosine facilitates gene expression in eukaryotic cells and is recognized by cap-binding proteins.
Cross-references
BRENDA2.1.1.56
EC2PDB2.1.1.56
ExplorEnz2.1.1.56
PRIAM enzyme-specific profiles2.1.1.56
KEGG Ligand Database for Enzyme Nomenclature2.1.1.56
IUBMB Enzyme Nomenclature2.1.1.56
IntEnz2.1.1.56
MEDLINEFind literature relating to 2.1.1.56
MetaCyc2.1.1.56
Rhea expert-curated reactions2.1.1.56
UniProtKB/Swiss-Prot
P11079, LMBD2_REOVDQ91RA4, LMBD2_REOVJQ91RA6, LMBD2_REOVL
Q6DN67, L_CPSVPQ8BCV9, L_MILVLQ8V2R8, MCEL_CAMPM
Q775U0, MCEL_CAMPSQ8QMV9, MCEL_CWPXBQ80DX6, MCEL_CWPXG
Q9J584, MCEL_FOWPNA0A7H0DN85, MCEL_MONPVP25950, MCEL_RFVKA
O57209, MCEL_VACCAP20979, MCEL_VACCCQ9JFA8, MCEL_VACCT
P04298, MCEL_VACCWP0DSX5, MCEL_VAR67P0DSX6, MCEL_VARV
Q9LHQ7, MCES1_ARATHQ6Z9U7, MCES1_ORYSJQ5HZ60, MCES2_ARATH
Q6K833, MCES2_ORYSJA1CT57, MCES_ASPCLQ4WN42, MCES_ASPFU
A2QVS9, MCES_ASPNCQ2UM19, MCES_ASPORQ61E36, MCES_CAEBR
Q9XVS1, MCES_CAEELQ5ADX5, MCES_CANALQ6FML4, MCES_CANGA
P0CO65, MCES_CRYNBP0CO64, MCES_CRYNJQ1MTD3, MCES_DANRE
Q6BMH4, MCES_DEBHAQ9VJQ4, MCES_DROMEQ8SR66, MCES_ENCCU
Q754U7, MCES_EREGSO72908, MCES_FOWPNO43148, MCES_HUMAN
Q6CKI0, MCES_KLULAA5E032, MCES_LODELQ4R7K1, MCES_MACFA
A4R8D7, MCES_MAGO7Q9D0L8, MCES_MOUSEA1DMG9, MCES_NEOFI
A5DDJ4, MCES_PICGUA3GEV2, MCES_PICSTQ5U2U7, MCES_RAT
O74880, MCES_SCHPOQ08512, MCES_SWPVKQ9I8S2, MCES_XENLA
Q28FT4, MCES_XENTRQ6CC11, MCES_YARLIP32783, MCES_YEAST
Q9QB92, MCES_YMTV5P32094, MCE_ASFB7P0C995, MCE_ASFK5
Q65216, MCE_ASFM2P0C993, MCE_ASFP4P0C994, MCE_ASFWA
Q5UQX1, MCE_MIMIVQ91B85, POLG_ALKVC8XPA8, POLG_BANV
Q32ZE0, POLG_BUSVP27909, POLG_DEN1BP33478, POLG_DEN1S
P17763, POLG_DEN1WP29990, POLG_DEN26P29991, POLG_DEN27
P14337, POLG_DEN28P07564, POLG_DEN2JP14340, POLG_DEN2N
P12823, POLG_DEN2PQ9WDA6, POLG_DEN2QQ99D35, POLG_DEN3C
Q5UB51, POLG_DEN3IQ6YMS3, POLG_DEN3MP27915, POLG_DEN3P
Q6YMS4, POLG_DEN3SP09866, POLG_DEN4DQ2YHF2, POLG_DEN4H
Q58HT7, POLG_DEN4PQ5UCB8, POLG_DEN4SQ2YHF0, POLG_DEN4T
C8XPB2, POLG_EHVQ32ZD7, POLG_ILHVP27395, POLG_JAEV1
P19110, POLG_JAEV5P32886, POLG_JAEVJG3FEX6, POLG_JAEVM
D7RF80, POLG_KFDVQ32ZD5, POLG_KOKVP14335, POLG_KUNJM
P29837, POLG_LANVTP22338, POLG_LIVP33515, POLG_MCFA
P05769, POLG_MVEV5Q7T6D2, POLG_OHFVQ04538, POLG_POWVL
Q32ZD4, POLG_ROCVP09732, POLG_STEVMQ01299, POLG_TBEVH
P07720, POLG_TBEVSP14336, POLG_TBEVWQ5WPU5, POLG_USUV
P06935, POLG_WNVQ9Q6P4, POLG_WNV9C5H431, POLG_WSLV
P03314, POLG_YEFV1Q6DV88, POLG_YEFVAQ6J3P1, POLG_YEFVC
Q074N0, POLG_YEFVEQ89277, POLG_YEFVFQ98803, POLG_YEFVI
Q1X881, POLG_YEFVNQ9YRV3, POLG_YEFVTQ1X880, POLG_YEFVU
Q32ZE1, POLG_ZIKVA0A024B7W1, POLG_ZIKVFA0A142I5B9, POLG_ZIKVK
P0C6W1, R1AB_BC133P0C6V9, R1AB_BC279P0C6W2, R1AB_BCHK3
P0C6W3, R1AB_BCHK4P0C6W4, R1AB_BCHK5P0C6W5, R1AB_BCHK9
P0C6W6, R1AB_BCRP3P0C6W7, R1AB_CVBENP0C6W8, R1AB_CVBLU
P0C6W9, R1AB_CVBMP0C6X0, R1AB_CVBQP0C6X2, R1AB_CVHN1
P0C6X3, R1AB_CVHN2P0C6X4, R1AB_CVHN5P0C6X6, R1AB_CVHOC
P0C6X8, R1AB_CVM2P0C6X9, R1AB_CVMA5P0C6Y0, R1AB_CVMJH
K9N7C7, R1AB_MERS1P0C6Y4, R1AB_PEDV7P0C6X7, R1AB_SARS
P0DTD1, R1AB_SARS2Q008X6, R1AB_WBV24Q008X5, R1A_WBV24
Q8VA43, VP1_AQRVAQ8JU62, VP1_AQRVCB2BND9, VP1_AQRVG
O56043, VP2_RRSVTQ9INI4, VP3_BAVJKQ7TDB4, VP3_MYRV9
Q3ZK57, VP3_ROT41B1NKR5, VP3_ROTADA9Q1K9, VP3_ROTB2
A7J3A0, VP3_ROTBNQ65526, VP3_ROTBSQ6WAT6, VP3_ROTBU
Q6WNV6, VP3_ROTCCQ6WNV7, VP3_ROTELA4ZCW6, VP3_ROTH3
Q6WNW3, VP3_ROTH6B1NKR1, VP3_ROTH7Q82041, VP3_ROTHC
Q6WNW5, VP3_ROTHDQ9QNB1, VP3_ROTHKB1NKS7, VP3_ROTHL
B1NKT1, VP3_ROTHPA7J392, VP3_ROTHSB1NKT9, VP3_ROTHT
Q91HJ9, VP3_ROTHUQ6WVH5, VP3_ROTHWQ45UF7, VP3_ROTJ1
Q6WNV8, VP3_ROTP5P26192, VP3_ROTPCQ8BB04, VP3_ROTRF
P15736, VP3_ROTS1A2T3S5, VP3_ROTSHB3F2X7, VP3_ROTTU
B2BMF9, VP3_ROTW3B1NKU3, VP3_ROTWIA7J3A4, VP3_ROTYO
Q91ID8, VP4_LDCPRQ2Y0E6, VP5_APRVF

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-