ID   2.1.1.57
DE   Methyltransferase cap1.
AN   Cap1-MTase.
AN   mRNA (nucleoside-2'-O)-methyltransferase.
CA   S-adenosyl-L-methionine + a 5'-(N(7)-methyl 5'-triphosphoguanosine)-
CA   (purine-ribonucleotide)-[mRNA] = S-adenosyl-L-homocysteine + a 5'-(N(7)-
CA   methyl 5'-triphosphoguanosine)-(2'-O-methyl-purine-ribonucleotide)-
CA   [mRNA].
CC   -!- This enzyme catalyzes the methylation of the ribose on the first
CC       transcribed nucleotide of mRNA or snRNA molecules, which may be
CC       either guanosine or adenosine.
CC   -!- This methylation event is known as cap1, and occurs in all mRNAs and
CC       snRNAs of higher eukaryotes, including insects, vertebrates and their
CC       viruses.
CC   -!- The human enzyme can also methylate mRNA molecules that lack
CC       methylation on the capping 5'-triphosphoguanosine.
CC   -!- Formerly EC 2.1.1.58.
DR   D2HRF1, CMTR1_AILME;  A2VE39, CMTR1_BOVIN;  Q803R5, CMTR1_DANRE;
DR   Q8N1G2, CMTR1_HUMAN;  Q9DBC3, CMTR1_MOUSE;  Q5R981, CMTR1_PONAB;
DR   Q5U2Z5, CMTR1_RAT  ;  Q6GQ76, CMTR1_XENLA;  P41469, CMTR_NPVAC ;
DR   P15916, MCE_FOWPN  ;  P68544, MCE_MYXVL  ;  P68545, MCE_MYXVU  ;
DR   P19748, MCE_SHEVK  ;  P23334, MCE_SWPVK  ;  Q76ZT1, MCE_VACCA  ;
DR   P21033, MCE_VACCC  ;  P07617, MCE_VACCW  ;  P33052, MCE_VAR67  ;
DR   A8XYX2, MTR1A_CAEBR;  Q9NAA5, MTR1_CAEEL ;  Q54WR1, MTR1_DICDI ;
DR   Q9W4N2, MTR1_DROME ;  A4HQI9, MTR1_LEIBR ;  Q4Q089, MTR1_LEIMA ;
DR   Q38AH0, MTR1_TRYB2 ;  Q4E123, MTR1_TRYCC ;  Q91B85, POLG_ALKV  ;
DR   C8XPA8, POLG_BANV  ;  Q32ZE0, POLG_BUSV  ;  P27909, POLG_DEN1B ;
DR   P33478, POLG_DEN1S ;  P17763, POLG_DEN1W ;  P29990, POLG_DEN26 ;
DR   P29991, POLG_DEN27 ;  P14337, POLG_DEN28 ;  P07564, POLG_DEN2J ;
DR   P14340, POLG_DEN2N ;  P12823, POLG_DEN2P ;  Q9WDA6, POLG_DEN2Q ;
DR   Q99D35, POLG_DEN3C ;  Q5UB51, POLG_DEN3I ;  Q6YMS3, POLG_DEN3M ;
DR   P27915, POLG_DEN3P ;  Q6YMS4, POLG_DEN3S ;  P09866, POLG_DEN4D ;
DR   Q2YHF2, POLG_DEN4H ;  Q58HT7, POLG_DEN4P ;  Q5UCB8, POLG_DEN4S ;
DR   Q2YHF0, POLG_DEN4T ;  C8XPB2, POLG_EHV   ;  Q32ZD7, POLG_ILHV  ;
DR   P27395, POLG_JAEV1 ;  P19110, POLG_JAEV5 ;  P32886, POLG_JAEVJ ;
DR   G3FEX6, POLG_JAEVM ;  D7RF80, POLG_KFDV  ;  Q32ZD5, POLG_KOKV  ;
DR   P14335, POLG_KUNJM ;  P29837, POLG_LANVT ;  P22338, POLG_LIV   ;
DR   P33515, POLG_MCFA  ;  P05769, POLG_MVEV5 ;  Q7T6D2, POLG_OHFV  ;
DR   Q04538, POLG_POWVL ;  Q32ZD4, POLG_ROCV  ;  P09732, POLG_STEVM ;
DR   Q01299, POLG_TBEVH ;  P07720, POLG_TBEVS ;  P14336, POLG_TBEVW ;
DR   Q5WPU5, POLG_USUV  ;  P06935, POLG_WNV   ;  Q9Q6P4, POLG_WNV9  ;
DR   C5H431, POLG_WSLV  ;  P03314, POLG_YEFV1 ;  Q6DV88, POLG_YEFVA ;
DR   Q6J3P1, POLG_YEFVC ;  Q074N0, POLG_YEFVE ;  Q89277, POLG_YEFVF ;
DR   Q98803, POLG_YEFVI ;  Q1X881, POLG_YEFVN ;  Q9YRV3, POLG_YEFVT ;
DR   Q1X880, POLG_YEFVU ;  Q32ZE1, POLG_ZIKV  ;  A0A024B7W1, POLG_ZIKVF ;
DR   A0A142I5B9, POLG_ZIKVK ;
//