ID   2.1.1.70
DE   8-hydroxyfuranocoumarin 8-O-methyltransferase.
AN   furanocoumarin 8-methyltransferase.
AN   furanocoumarin 8-O-methyl-transferase.
AN   xanthotoxol 8-O-methyltransferase.
AN   XMT.
CA   (1) an 8-hydroxyfurocoumarin + S-adenosyl-L-methionine =
CA   an 8-methoxyfurocoumarin + H(+) + S-adenosyl-L-homocysteine.
CA   (2) S-adenosyl-L-methionine + xanthotoxol = H(+) + S-adenosyl-L-
CA   homocysteine + xanthotoxin.
CC   -!- Converts xanthotoxol into xanthotoxin, which has therapeutic
CC       potential in the treatment of psoriasis as it has photosensitizing
CC       and antiproliferative activities.
CC   -!- Methylates the 8-hydroxy group of some hydroxy- and methylcoumarins,
CC       but has little activity on non-coumarin phenols.
CC   -!- See also EC 2.1.1.69.
CC   -!- Formerly EC 2.1.1.93.
DR   A0A4P8DY91, COMTS_KITPR;
//