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ENZYME

ENZYME entry: EC 2.1.1.77

Accepted Name
protein-L-isoaspartate(D-aspartate) O-methyltransferase
Alternative Name(s)
L-isoaspartyl protein carboxyl methyltransferase
protein beta-aspartate O-methyltransferase
protein D-aspartate methyltransferase
protein L-isoaspartyl methyltransferase
Reaction catalysed
[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine
Comment(s)
  • D-aspartate (but not L-aspartate) residues in proteins can also act as acceptors.
  • Formerly EC 2.1.1.24.
Cross-references
BRENDA2.1.1.77
EC2PDB2.1.1.77
ExplorEnz2.1.1.77
PRIAM enzyme-specific profiles2.1.1.77
KEGG Ligand Database for Enzyme Nomenclature2.1.1.77
IUBMB Enzyme Nomenclature2.1.1.77
IntEnz2.1.1.77
MEDLINEFind literature relating to 2.1.1.77
MetaCyc2.1.1.77
Rhea expert-curated reactions2.1.1.77
UniProtKB/Swiss-Prot
A7HC32, PIMT1_ANADFQ42539, PIMT1_ARATHO30199, PIMT1_ARCFU
Q0KB67, PIMT1_CUPNHA5GEF7, PIMT1_GEOURA1TZ54, PIMT1_MARN8
Q8TT93, PIMT1_METACQ2YCR1, PIMT1_NITMUQ3JCZ3, PIMT1_NITOC
A1ASL8, PIMT1_PELPDQ12A85, PIMT1_POLSJQ2J302, PIMT1_RHOP2
A8FST4, PIMT1_SHESHA0LL58, PIMT1_SYNFMA7HHV3, PIMT2_ANADF
Q64J17, PIMT2_ARATHO27962, PIMT2_ARCFUQ0K951, PIMT2_CUPNH
A5G4S7, PIMT2_GEOURA1U4P7, PIMT2_MARN8Q8TT94, PIMT2_METAC
Q2YBR7, PIMT2_NITMUQ3JAW6, PIMT2_NITOCA1ASW6, PIMT2_PELPD
Q123X2, PIMT2_POLSJQ2IWH1, PIMT2_RHOP2A8FX24, PIMT2_SHESH
A0LM89, PIMT2_SYNFMA5G6S0, PIMT3_GEOURA0KGH9, PIMT_AERHH
Q9YDA1, PIMT_AERPEA4SRB5, PIMT_AERS4B6JFP0, PIMT_AFIC5
Q0VQD1, PIMT_ALCBSQ5E332, PIMT_ALIF1B5FAF3, PIMT_ALIFM
B6EKL2, PIMT_ALISLQ0A7L5, PIMT_ALKEHB4RZG8, PIMT_ALTMD
B8J9E3, PIMT_ANAD2Q2IIL9, PIMT_ANADEQ5P833, PIMT_AROAE
A8I4G3, PIMT_AZOC5A1K4F0, PIMT_AZOSBQ2L008, PIMT_BORA1
Q7WI37, PIMT_BORBRQ7W671, PIMT_BORPAA9IP04, PIMT_BORPD
P15246, PIMT_BOVINA5EJV5, PIMT_BRASBA4YV66, PIMT_BRASO
A6X6Y1, PIMT_BRUA4B1YRE4, PIMT_BURA4A0K7U6, PIMT_BURCH
Q0BEV7, PIMT_BURCMQ39FP9, PIMT_BURL3A3MK86, PIMT_BURM7
A2S291, PIMT_BURM9Q62JV3, PIMT_BURMAA1V4L2, PIMT_BURMS
B1JTA2, PIMT_BURO0Q1BGY4, PIMT_BURO1A3NVY1, PIMT_BURP0
Q3JRP1, PIMT_BURP1A3NA64, PIMT_BURP6Q63UU3, PIMT_BURPS
Q2SWF4, PIMT_BURTAA4JEQ0, PIMT_BURVGQ27873, PIMT_CAEEL
B0T1Q1, PIMT_CAUSKQ9A6T6, PIMT_CAUVCB8GX51, PIMT_CAUVN
B3PJA8, PIMT_CELJUA3PIZ8, PIMT_CERS1Q3J3D1, PIMT_CERS4
A4WU05, PIMT_CERS5B9KQZ1, PIMT_CERSKQ5F3N1, PIMT_CHICK
B3EEX3, PIMT_CHLL2Q3B1L6, PIMT_CHLL3B3QQM1, PIMT_CHLP8
B3ELJ9, PIMT_CHLPBA1BDC1, PIMT_CHLPDA4SGH4, PIMT_CHLPM
Q8KFW8, PIMT_CHLTEA0LZ51, PIMT_CHRFKQ1QU77, PIMT_CHRSD
Q7NRV0, PIMT_CHRVOA8ANV7, PIMT_CITK8Q487E5, PIMT_COLP3
A7MJ61, PIMT_CROS8Q46ZH2, PIMT_CUPPJQ11TS0, PIMT_CYTH3
Q92047, PIMT_DANREQ47D25, PIMT_DECARB8J017, PIMT_DESDA
A8ZXR8, PIMT_DESOHQ6ARM1, PIMT_DESPSQ9GPS6, PIMT_DICDI
B5YF00, PIMT_DICT6B8E0T1, PIMT_DICTDA8LQK6, PIMT_DINSH
Q27869, PIMT_DROMEA7ZQI7, PIMT_ECO24B7UHG2, PIMT_ECO27
B7MKL7, PIMT_ECO45B7LEG1, PIMT_ECO55P0A7A6, PIMT_ECO57
B5Z3A5, PIMT_ECO5EB7NT87, PIMT_ECO7IB7MZ44, PIMT_ECO81
B7LXF5, PIMT_ECO8AC4ZZP7, PIMT_ECOBWB1XCR9, PIMT_ECODH
A8A3M2, PIMT_ECOHSA1AET7, PIMT_ECOK1Q8FEJ8, PIMT_ECOL6
B1IUT6, PIMT_ECOLCP0A7A5, PIMT_ECOLIB7N6X3, PIMT_ECOLU
B6I6D3, PIMT_ECOSEB1LQ63, PIMT_ECOSMQ1R7U8, PIMT_ECOUT
A4WDU8, PIMT_ENT38B2VG25, PIMT_ERWT9B7LWJ2, PIMT_ESCF3
A7HL14, PIMT_FERNBA5FEA5, PIMT_FLAJ1A6H0V1, PIMT_FLAPJ
Q39VS0, PIMT_GEOMGQ74CZ5, PIMT_GEOSLQ7NJY2, PIMT_GLOVI
Q2SKW3, PIMT_HAHCHA1WWY5, PIMT_HALHLB6JMT1, PIMT_HELP2
B5Z887, PIMT_HELPGQ9ZKC2, PIMT_HELPJP56133, PIMT_HELPY
A9AUP1, PIMT_HERA2A4G4J3, PIMT_HERARP22061, PIMT_HUMAN
A2BKH8, PIMT_HYPBUQ5QUB2, PIMT_IDILOA8AAV7, PIMT_IGNH4
A6SZX9, PIMT_JANMAQ28TH8, PIMT_JANSCB5XV38, PIMT_KLEP3
A6TD35, PIMT_KLEP7B1L6T9, PIMT_KORCOQ1INS6, PIMT_KORVE
Q1MRE5, PIMT_LAWIPB1Y0T0, PIMT_LEPCPQ4R5H0, PIMT_MACFA
A0L4K5, PIMT_MAGMMQ0ANE2, PIMT_MARMMC6BTT9, PIMT_MARSD
A6UWM1, PIMT_META3Q0W2W0, PIMT_METARA7I4W9, PIMT_METB6
Q12UV0, PIMT_METBUA9VY77, PIMT_METEPQ1H095, PIMT_METFK
Q2FRW3, PIMT_METHJQ57636, PIMT_METJAQ8TYL4, PIMT_METKA
A4G087, PIMT_METM5A9A8I9, PIMT_METM6A6VI91, PIMT_METM7
Q8PW90, PIMT_METMAA3CXP8, PIMT_METMJQ6M116, PIMT_METMP
B1ZJW1, PIMT_METPBA2SF76, PIMT_METPPO26915, PIMT_METTH
A0B9U1, PIMT_METTPA6UR90, PIMT_METVSP23506, PIMT_MOUSE
Q1D6W9, PIMT_MYXXDB2A578, PIMT_NATTJQ0ADP2, PIMT_NITEC
Q82VW0, PIMT_NITEUQ72AZ1, PIMT_NITV2A1VD15, PIMT_NITV4
B8DJP7, PIMT_NITV9Q3SRQ7, PIMT_NITWNQ30ZM2, PIMT_OLEA2
B1ZPF0, PIMT_OPITPA1B5M0, PIMT_PARDPA7HXK6, PIMT_PARL1
Q2W4A2, PIMT_PARM1B2JG67, PIMT_PARP8Q6MCW9, PIMT_PARUW
Q6D1B6, PIMT_PECASC6DDF9, PIMT_PECCPB4SFU3, PIMT_PELPB
A5CYQ6, PIMT_PELTSA9BH07, PIMT_PETMOQ7N8K3, PIMT_PHOLL
Q6LMT7, PIMT_PHOPRB1XQE1, PIMT_PICP2P80895, PIMT_PIG
Q5RA89, PIMT_PONABB4F223, PIMT_PROMHQ48F88, PIMT_PSE14
Q15P27, PIMT_PSEA6A6V1G4, PIMT_PSEA7B7V8C3, PIMT_PSEA8
Q02R96, PIMT_PSEABP45683, PIMT_PSEAEQ1I655, PIMT_PSEE4
Q4KHE7, PIMT_PSEF5C3K706, PIMT_PSEFSA4XWR1, PIMT_PSEMY
A5W820, PIMT_PSEP1Q3KH83, PIMT_PSEPFB0KSC8, PIMT_PSEPG
Q88MF0, PIMT_PSEPKB1JB29, PIMT_PSEPWQ886L4, PIMT_PSESM
Q3IDD2, PIMT_PSET1Q4ZWP9, PIMT_PSEU2Q9UXX0, PIMT_PYRAB
Q8ZYN0, PIMT_PYRAEA4WNC5, PIMT_PYRARA3MY16, PIMT_PYRCJ
Q8TZR3, PIMT_PYRFUO59534, PIMT_PYRHOA1RSC6, PIMT_PYRIL
B1YC47, PIMT_PYRNVQ8Y039, PIMT_RALN1P22062, PIMT_RAT
O08249, PIMT_RHIMEB6ISM3, PIMT_RHOCSQ07N42, PIMT_RHOP5
Q6NCU3, PIMT_RHOPAQ214W4, PIMT_RHOPBQ136H9, PIMT_RHOPS
Q2RTH7, PIMT_RHORTA7NI01, PIMT_ROSCSQ163U2, PIMT_ROSDO
A5UZW2, PIMT_ROSS1Q5LQ09, PIMT_RUEPOQ1GFP1, PIMT_RUEST
Q21LB7, PIMT_SACD2B5F407, PIMT_SALA4A9MF32, PIMT_SALAR
Q57KJ8, PIMT_SALCHB5FTS1, PIMT_SALDCB5QW14, PIMT_SALEP
B5RDP9, PIMT_SALG2B4TFW3, PIMT_SALHSB4T453, PIMT_SALNS
Q5PEE9, PIMT_SALPAA9N1H6, PIMT_SALPBC0PXA3, PIMT_SALPC
B5BEY0, PIMT_SALPKQ2S176, PIMT_SALRDB4TTV7, PIMT_SALSV
Q8Z474, PIMT_SALTIQ8ZMF9, PIMT_SALTYQ9URZ1, PIMT_SCHPO
A8G9Z6, PIMT_SERP5A1S4E3, PIMT_SHEAMB8E8T7, PIMT_SHEB2
A3D789, PIMT_SHEB5A6WR22, PIMT_SHEB8A9KYG4, PIMT_SHEB9
Q12PY8, PIMT_SHEDOQ086A4, PIMT_SHEFNB0TK10, PIMT_SHEHH
A3QC83, PIMT_SHELPQ8EBR6, PIMT_SHEONA8H1T1, PIMT_SHEPA
A4Y937, PIMT_SHEPCB8CJQ2, PIMT_SHEPWA0KU88, PIMT_SHESA
Q0HL66, PIMT_SHESMQ0HXG4, PIMT_SHESRA1RHF9, PIMT_SHESW
B1KPT0, PIMT_SHEWMB2TZI8, PIMT_SHIB3Q31XA5, PIMT_SHIBS
Q32CI7, PIMT_SHIDSQ0T1H4, PIMT_SHIF8Q83JY3, PIMT_SHIFL
Q3YYB9, PIMT_SHISSQ2NVM1, PIMT_SODGMA3DMG3, PIMT_STAMF
B4SR93, PIMT_STRM5B2FK95, PIMT_STRMKA4VJV3, PIMT_STUS1
Q2LUT4, PIMT_SYNASQ3A4N4, PIMT_SYNC1Q2JJN4, PIMT_SYNJB
A6LNM3, PIMT_THEM4Q56308, PIMT_THEMAB6YX51, PIMT_THEON
C6A3F2, PIMT_THESMQ3SKJ2, PIMT_THIDAB3E6I4, PIMT_TRIL1
B7VK62, PIMT_VIBA3A7MTT6, PIMT_VIBC1A5F9C1, PIMT_VIBC3
Q9KUI8, PIMT_VIBCHC3LS22, PIMT_VIBCMQ87LQ6, PIMT_VIBPA
Q8DC56, PIMT_VIBVUQ7MHQ8, PIMT_VIBVYQ43209, PIMT_WHEAT
Q8PLR3, PIMT_XANACQ4UTP9, PIMT_XANC8B0RTZ8, PIMT_XANCB
Q8P9Y6, PIMT_XANCPQ3BUS3, PIMT_XANE5Q2P1L5, PIMT_XANOM
B2SUB3, PIMT_XANOPQ5GYL2, PIMT_XANORA7INP1, PIMT_XANP2
B2I8X8, PIMT_XYLF2Q9PF21, PIMT_XYLFAB0U4U6, PIMT_XYLFM
Q87AK5, PIMT_XYLFTA1JJT8, PIMT_YERE8A7FLX4, PIMT_YERP3
Q1C474, PIMT_YERPAB2K581, PIMT_YERPBQ8ZBQ0, PIMT_YERPE
A9R115, PIMT_YERPGQ1CLR2, PIMT_YERPNA4TQ01, PIMT_YERPP
Q66EB9, PIMT_YERPSB1JJF4, PIMT_YERPY

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-