ENZYME entry: EC 2.1.1.90
| Accepted Name |
|---|
| Methanol--corrinoid protein Co-methyltransferase.
|
| Alternative Name(s) |
|---|
| Methanol--5-hydroxybenzimidazolylcobamide Co-methyltransferase. |
| Reaction catalysed |
|---|
| Methanol + a [Co(I) methanol-specific corrinoid protein] <=> a [methyl-Co(III) methanol-specific corrinoid protein] + H(2)O |
| Comment(s) |
|---|
- The enzyme, which catalyzes the transfer of methyl groups from
methanol to a methanol-specific corrinoid protein (MtaC), is involved
in methanogenesis from methanol.
- Methylation of the corrinoid protein requires the central cobalt to
be in the Co(I) state.
- During methylation the cobalt is oxidized to the Co(III) state.
- Free cob(I)alamin can substitute for the corrinoid protein in vitro.
- Inactivated by oxygen and other oxidizing agents, and reactivated by
catalytic amounts of ATP and hydrogen.
|
| Cross-references |
|---|
| BRENDA | 2.1.1.90 |
| EC2PDB | 2.1.1.90 |
| ExplorEnz | 2.1.1.90 |
| PRIAM enzyme-specific profiles | 2.1.1.90 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.1.1.90 |
| IUBMB Enzyme Nomenclature | 2.1.1.90 |
| IntEnz | 2.1.1.90 |
| MEDLINE | Find literature relating to 2.1.1.90 |
| MetaCyc | 2.1.1.90 |
| UniProtKB/Swiss-Prot |
|
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