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ENZYME entry: EC 2.1.1.99

Accepted Name
3-hydroxy-16-methoxy-2,3-dihydrotabersonine N-methyltransferase.
Alternative Name(s)
16-methoxy-2,3-dihydro-3-hydroxytabersonine methyltransferase.
16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase.
NMT.
S-adenosyl-L-methionine:16-methoxy-2,3-dihydro-3-hydroxytabersonine N-methyltransferase.
Reaction catalysed
(3R)-3-hydroxy-16-methoxy-2,3-dihydrotabersonine + S-adenosyl-L-methionine <=> deacetoxyvindoline + H(+) + S-adenosyl-L-homocysteine
Comment(s)
Involved in the biosynthesis of vindoline from tabersonine in the Madagascar periwinkle Catharanthus roseus.
Cross-references
BRENDA2.1.1.99
EC2PDB2.1.1.99
ExplorEnz2.1.1.99
PRIAM enzyme-specific profiles2.1.1.99
KEGG Ligand Database for Enzyme Nomenclature2.1.1.99
IUBMB Enzyme Nomenclature2.1.1.99
IntEnz2.1.1.99
MEDLINEFind literature relating to 2.1.1.99
MetaCyc2.1.1.99
Rhea expert-curated reactions2.1.1.99
UniProtKB/Swiss-Prot
W5U2K2, NMT_CATRO

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