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ENZYME

ENZYME entry: EC 2.1.2.3

PURL: https://purl.expasy.org/enzyme/EC/2.1.2.3
Accepted Name
phosphoribosylaminoimidazolecarboxamide formyltransferase
Alternative Name(s)
10-formyltetrahydrofolate:5'-phosphoribosyl-5-amino-4- imidazolecarboxamide formyltransferase
5'-phosphoribosyl-5-amino-4-imidazolecarboxamide formyltransferase
5-amino-1-ribosyl-4-imidazolecarboxamide 5'-phosphate transformylase
5-amino-4-imidazolecarboxamide ribonucleotide transformylase
5-amino-4-imidazolecarboxamide ribotide transformylase
AICAR formyltransferase
AICAR transformylase
aminoimidazolecarboxamide ribonucleotide transformylase
Reaction catalysed
(6R)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide + (6S)-5,6,7,8-tetrahydrofolate
Cross-references
BRENDA2.1.2.3
EC2PDB2.1.2.3
ExplorEnz2.1.2.3
KEGG Ligand Database for Enzyme Nomenclature2.1.2.3
IUBMB Enzyme Nomenclature2.1.2.3
MEDLINEFind literature relating to 2.1.2.3
MetaCyc2.1.2.3
Rhea expert-curated reactions2.1.2.3
UniProtKB/Swiss-Prot
P54113, PUR91_YEASTP38009, PUR92_YEASTB0BZH9, PUR9_ACAM1
A3DEU9, PUR9_ACET2A5FUH4, PUR9_ACICJB7J5P7, PUR9_ACIF2
B5EL42, PUR9_ACIF5A0KGJ2, PUR9_AERHHA4SR98, PUR9_AERS4
Q8UBM8, PUR9_AGRFCQ0VMY5, PUR9_ALCBSQ5E257, PUR9_ALIF1
B5FC70, PUR9_ALIFMB6ENA8, PUR9_ALISLA6TLS7, PUR9_ALKMQ
A8MLI9, PUR9_ALKOOQ46480, PUR9_ALLVDB4S133, PUR9_ALTMD
B8JHC9, PUR9_ANAD2Q2IKQ7, PUR9_ANADEA7HA60, PUR9_ANADF
B4UJ61, PUR9_ANASKB7GFU2, PUR9_ANOFWO67775, PUR9_AQUAE
C1DLJ1, PUR9_AZOVDC3PBN4, PUR9_BACAAC3L536, PUR9_BACAC
A0R900, PUR9_BACAHQ81ZG8, PUR9_BACANB7JM89, PUR9_BACC0
Q73EN1, PUR9_BACC1B7IUV7, PUR9_BACC2C1EV67, PUR9_BACC3
B7H4U0, PUR9_BACC4B7HS36, PUR9_BACC7A7GKI2, PUR9_BACCN
B9J1K9, PUR9_BACCQQ81IP9, PUR9_BACCRQ63GS9, PUR9_BACCZ
Q6HPA0, PUR9_BACHKA9VRF5, PUR9_BACMKP12048, PUR9_BACSU
Q8A155, PUR9_BACTNA1UR09, PUR9_BARBKQ6G5S5, PUR9_BARHE
Q6FYG4, PUR9_BARQUA9IZD0, PUR9_BART1Q1LU51, PUR9_BAUCH
B3DRY6, PUR9_BIFLDQ8G6B1, PUR9_BIFLOQ0VCK0, PUR9_BOVIN
Q89WU7, PUR9_BRADUC0QXU6, PUR9_BRAHWB2S7P0, PUR9_BRUA1
Q2YLH0, PUR9_BRUA2A6WXV3, PUR9_BRUA4Q57B71, PUR9_BRUAB
A9M854, PUR9_BRUC2C0RF67, PUR9_BRUMBP67539, PUR9_BRUME
A5VSF8, PUR9_BRUO2A9WWU1, PUR9_BRUSIP67540, PUR9_BRUSU
B8D8J3, PUR9_BUCA5P57143, PUR9_BUCAIQ8KA70, PUR9_BUCAP
B8D6U7, PUR9_BUCATQ89B23, PUR9_BUCBPB1YTE2, PUR9_BURA4
A0K4L7, PUR9_BURCHB4EES4, PUR9_BURCJQ0BI80, PUR9_BURCM
Q39JI8, PUR9_BURL3A9AH70, PUR9_BURM1A3MP76, PUR9_BURM7
A2S597, PUR9_BURM9Q62HA6, PUR9_BURMAA1V068, PUR9_BURMS
B1JVV6, PUR9_BURO0Q1BZ33, PUR9_BURO1A3NZ64, PUR9_BURP0
Q3JNS8, PUR9_BURP1A3NDF2, PUR9_BURP6Q63QX8, PUR9_BURPS
Q2SZ52, PUR9_BURTAA4JBL5, PUR9_BURVGB9MS89, PUR9_CALBD
Q8RC55, PUR9_CALS4A4XKZ2, PUR9_CALS8A7ZCZ7, PUR9_CAMC1
A7GYY6, PUR9_CAMC5A8FM07, PUR9_CAMJ8A7H375, PUR9_CAMJD
Q9PNY2, PUR9_CAMJEA1VZU4, PUR9_CAMJJQ5HUK6, PUR9_CAMJR
Q9ABY4, PUR9_CAUVCA3PNE9, PUR9_CERS1Q3IYU8, PUR9_CERS4
A4WWQ0, PUR9_CERS5B9KP36, PUR9_CERSKQ11CT4, PUR9_CHESB
P31335, PUR9_CHICKA9WEK8, PUR9_CHLAAQ3ATZ1, PUR9_CHLCH
B3EEI0, PUR9_CHLL2Q3B5R1, PUR9_CHLL3B3QQA5, PUR9_CHLP8
B3ELV3, PUR9_CHLPBA1BE85, PUR9_CHLPDA4SDE6, PUR9_CHLPM
B3QS62, PUR9_CHLT3Q8KFK6, PUR9_CHLTEQ7P0M1, PUR9_CHRVO
B5EBF9, PUR9_CITBBA8AKS0, PUR9_CITK8Q97J91, PUR9_CLOAB
A7FXD3, PUR9_CLOB1C3L2U9, PUR9_CLOB6A6LSB3, PUR9_CLOB8
B2V3C3, PUR9_CLOBAB2TN76, PUR9_CLOBBA5I5V9, PUR9_CLOBH
C1FV76, PUR9_CLOBJB1IL57, PUR9_CLOBKA7GH96, PUR9_CLOBL
B1KZ55, PUR9_CLOBMQ18CW0, PUR9_CLOD6B9E4K6, PUR9_CLOK1
A5N0Q0, PUR9_CLOK5A0Q1J0, PUR9_CLONNQ0TTB0, PUR9_CLOP1
Q8XMK2, PUR9_CLOPEQ0SV48, PUR9_CLOPSQ892X3, PUR9_CLOTE
Q489F4, PUR9_COLP3C3PF03, PUR9_CORA7Q9RHX6, PUR9_CORAM
Q6NID8, PUR9_CORDIQ8FR29, PUR9_COREFA4QCK4, PUR9_CORGB
Q8NS21, PUR9_CORGLA7MJ89, PUR9_CROS8J9VJP1, PUR9_CRYNH
Q1LRB3, PUR9_CUPMCQ0KEC0, PUR9_CUPNHQ475R4, PUR9_CUPPJ
B2AH76, PUR9_CUPTRQ6A6Y8, PUR9_CUTAKB8HPG4, PUR9_CYAP4
C1CWJ7, PUR9_DEIDVQ1J119, PUR9_DEIGDQ9RW01, PUR9_DEIRA
B8FP05, PUR9_DESHDQ24QH6, PUR9_DESHYQ86L14, PUR9_DICDI
A8LMD0, PUR9_DINSHA7ZUM3, PUR9_ECO24B7UPG1, PUR9_ECO27
B7MIZ2, PUR9_ECO45B7LAV3, PUR9_ECO55Q8X611, PUR9_ECO57
B5Z0A3, PUR9_ECO5EB7NRT9, PUR9_ECO7IB7MRD0, PUR9_ECO81
B7M7R5, PUR9_ECO8AC5A0U7, PUR9_ECOBWB1XC09, PUR9_ECODH
A8A7A6, PUR9_ECOHSA1AIH7, PUR9_ECOK1Q0TA59, PUR9_ECOL5
Q8FB68, PUR9_ECOL6B1IUP1, PUR9_ECOLCP15639, PUR9_ECOLI
B7NFU7, PUR9_ECOLUB6I5L8, PUR9_ECOSEB1LPG6, PUR9_ECOSM
Q1R5X1, PUR9_ECOUTA4XQ60, PUR9_ECTM1B2KCF7, PUR9_ELUMP
Q833Z3, PUR9_ENTFAB2VG81, PUR9_ERWT9B7LUJ6, PUR9_ESCF3
Q8REV6, PUR9_FUSNNB9M4Q6, PUR9_GEODFQ39RK1, PUR9_GEOMG
Q74FJ9, PUR9_GEOSLC6E5Z3, PUR9_GEOSMA5G879, PUR9_GEOUR
B7KGS0, PUR9_GLOC7P43852, PUR9_HAEINQ9KF53, PUR9_HALH5
B0TEC5, PUR9_HELMIA4G1U6, PUR9_HERARQ0I557, PUR9_HISS1
B0UWT1, PUR9_HISS2P31939, PUR9_HUMANQ31II8, PUR9_HYDCU
A6SUQ1, PUR9_JANMAQ28K03, PUR9_JANSCB5XYD2, PUR9_KLEP3
A6TGR3, PUR9_KLEP7Q5FIV5, PUR9_LACACB3WF93, PUR9_LACCB
Q1G9G2, PUR9_LACDAQ049M1, PUR9_LACDBQ9CFG0, PUR9_LACLA
A2RJY0, PUR9_LACLMQ02Y66, PUR9_LACLSQ037V3, PUR9_LACP3
Q88U29, PUR9_LACPLC1D6F1, PUR9_LARHHQ38XW3, PUR9_LATSS
Q6AD62, PUR9_LEIXXB0SGW3, PUR9_LEPBAQ04T56, PUR9_LEPBJ
Q051H8, PUR9_LEPBLB0SQ10, PUR9_LEPBPQ72RT5, PUR9_LEPIC
Q8F3W6, PUR9_LEPINB1MY42, PUR9_LEUCKQ03Y85, PUR9_LEUMM
Q1WU55, PUR9_LIGS1A5VHU2, PUR9_LIMRDB2G5C2, PUR9_LIMRJ
Q92AP3, PUR9_LISINC1KW64, PUR9_LISMCQ71YQ3, PUR9_LISMF
B8DDZ2, PUR9_LISMHQ8Y6C5, PUR9_LISMOA0AJL9, PUR9_LISW6
B1HTV8, PUR9_LYSSCB9EAZ2, PUR9_MACCJA0LDB0, PUR9_MAGMM
Q1H4G7, PUR9_METFKB0JL55, PUR9_MICANQ2RGU9, PUR9_MOOTA
Q9CWJ9, PUR9_MOUSEP67542, PUR9_MYCBOA1KH91, PUR9_MYCBP
C1ALU3, PUR9_MYCBTB8ZU05, PUR9_MYCLBQ9Z5H5, PUR9_MYCLE
B2HEC3, PUR9_MYCMMQ9RAJ5, PUR9_MYCPAA3Q5N7, PUR9_MYCSJ
A1UL88, PUR9_MYCSKQ1B3W0, PUR9_MYCSSA5U0Z7, PUR9_MYCTA
P9WHM6, PUR9_MYCTOP9WHM7, PUR9_MYCTUA0PWC5, PUR9_MYCUA
Q1D898, PUR9_MYXXDB2A5W1, PUR9_NATTJQ5F6T1, PUR9_NEIG1
B4RP71, PUR9_NEIG2A9M4I2, PUR9_NEIM0Q9JUQ8, PUR9_NEIMA
Q9JZM7, PUR9_NEIMBA1KTP9, PUR9_NEIMFQ3JC90, PUR9_NITOC
A1SMP8, PUR9_NOCSJB2IX54, PUR9_NOSP7Q8YSJ2, PUR9_NOSS1
Q8CXK7, PUR9_OCEIHQ04EU6, PUR9_OENOBA1B5K8, PUR9_PARDP
A7HSQ6, PUR9_PARL1Q7TTX6, PUR9_PARMWB2JGU1, PUR9_PARP8
B2SYJ7, PUR9_PARPJQ13UC4, PUR9_PARXLP57828, PUR9_PASMU
Q6DAL2, PUR9_PECASC6DHT5, PUR9_PECCPQ03E83, PUR9_PEDPA
B4SDT6, PUR9_PELPBA1AS76, PUR9_PELPDC0QRH2, PUR9_PERMH
A9BIX9, PUR9_PETMOQ7N954, PUR9_PHOLLA4T025, PUR9_POLAQ
B1XS23, PUR9_POLNSQ5R5C2, PUR9_PONABB4S3H9, PUR9_PROA2
A3PAY7, PUR9_PROM0A2C098, PUR9_PROM1A8G2S6, PUR9_PROM2
A2CCK6, PUR9_PROM3A9BDN8, PUR9_PROM4A2BUP7, PUR9_PROM5
Q31CR6, PUR9_PROM9Q7VDS0, PUR9_PROMAB4EYT2, PUR9_PROMH
Q7TUM7, PUR9_PROMMQ7TUG1, PUR9_PROMPA2BP65, PUR9_PROMS
Q46HA8, PUR9_PROMTB7V1R6, PUR9_PSEA8Q02FG6, PUR9_PSEAB
Q9HUV9, PUR9_PSEAEQ1I4C1, PUR9_PSEE4Q4KIX5, PUR9_PSEF5
C3K6E0, PUR9_PSEFSA5W9K7, PUR9_PSEP1A6VCW0, PUR9_PSEP7
B0KJZ6, PUR9_PSEPGQ88DK3, PUR9_PSEPKB1J5T3, PUR9_PSEPW
Q87VR9, PUR9_PSESMQ3IIC3, PUR9_PSET1Q4FRN8, PUR9_PSYA2
Q1QA75, PUR9_PSYCKA1SZJ2, PUR9_PSYINA5WFX4, PUR9_PSYWF
Q8Y232, PUR9_RALN1B2UFL5, PUR9_RALPJO35567, PUR9_RAT
B3PS36, PUR9_RHIE6Q2K2T6, PUR9_RHIECQ1MA35, PUR9_RHIJ3
Q98ES7, PUR9_RHILOB5ZV31, PUR9_RHILWQ92KX6, PUR9_RHIME
B9JEU9, PUR9_RHIR8Q7UKJ8, PUR9_RHOBAQ2RN46, PUR9_RHORT
B7K3N8, PUR9_RIPO1Q16CE0, PUR9_ROSDOQ5LN38, PUR9_RUEPO
Q1GKJ2, PUR9_RUESTB8I490, PUR9_RUMCHB5F1I9, PUR9_SALA4
A9MHC3, PUR9_SALARB5FQM1, PUR9_SALDCB5QYG1, PUR9_SALEP
B5RFH8, PUR9_SALG2B4TDF3, PUR9_SALHSB4T108, PUR9_SALNS
Q5PKA9, PUR9_SALPAA9N0L8, PUR9_SALPBC0Q2T8, PUR9_SALPC
B5BJS5, PUR9_SALPKB4TQL6, PUR9_SALSVQ8Z335, PUR9_SALTI
P26978, PUR9_SALTYO74928, PUR9_SCHPOA8G8G3, PUR9_SERP5
A1S2J9, PUR9_SHEAMQ12IP4, PUR9_SHEDOQ088G0, PUR9_SHEFN
B0TR91, PUR9_SHEHHA3QII0, PUR9_SHELPQ8EJM1, PUR9_SHEON
A8GZM3, PUR9_SHEPAB8CTW4, PUR9_SHEPWA8FQD4, PUR9_SHESH
B1KNA0, PUR9_SHEWMB2TWJ3, PUR9_SHIB3Q31TZ1, PUR9_SHIBS
Q32AH9, PUR9_SHIDSQ0SXZ4, PUR9_SHIF8Q83IR9, PUR9_SHIFL
Q3YUX8, PUR9_SHISSQ5WJ82, PUR9_SHOC1C3MAR5, PUR9_SINFN
A6UED3, PUR9_SINMWQ2NWQ7, PUR9_SODGMA9GIT1, PUR9_SORC5
A6U0P1, PUR9_STAA2Q2FI05, PUR9_STAA3Q2FZI6, PUR9_STAA8
A5IRW0, PUR9_STAA9Q2YX50, PUR9_STAABQ5HH11, PUR9_STAAC
A6QFT1, PUR9_STAAEP67543, PUR9_STAAMP67544, PUR9_STAAN
Q6GI11, PUR9_STAARQ6GAE0, PUR9_STAASQ8NX88, PUR9_STAAW
B9DQ42, PUR9_STACTQ5HQ97, PUR9_STAEQQ8CT27, PUR9_STAES
Q4L582, PUR9_STAHJQ49WJ7, PUR9_STAS1Q3K3Z7, PUR9_STRA1
P67545, PUR9_STRA3P67546, PUR9_STRA5Q9KY50, PUR9_STRCO
C0MB61, PUR9_STRE4A8AUA2, PUR9_STRGCB4SL92, PUR9_STRM5
B2FJP9, PUR9_STRMKQ8DWK8, PUR9_STRMUQ04N19, PUR9_STRP2
P0DD60, PUR9_STRP3B5E5J9, PUR9_STRP4Q5XEF2, PUR9_STRP6
C1C9V4, PUR9_STRP7Q8P310, PUR9_STRP8Q1JE78, PUR9_STRPB
Q1JP34, PUR9_STRPCQ1JJ80, PUR9_STRPDQ1J934, PUR9_STRPF
B1I7V8, PUR9_STRPIB8ZJN3, PUR9_STRPJQ48VY9, PUR9_STRPM
Q97T99, PUR9_STRPNP0DD61, PUR9_STRPQB5XJ20, PUR9_STRPZ
Q8DRM1, PUR9_STRR6A4VYK5, PUR9_STRS2C0MC89, PUR9_STRS7
Q9F1T4, PUR9_STRSUA4VSB5, PUR9_STRSYQ03MZ6, PUR9_STRTD
B9DSR6, PUR9_STRU0C1CBM7, PUR9_STRZJC1CHW2, PUR9_STRZP
C1CNS9, PUR9_STRZTA4VPK9, PUR9_STUS1Q67KG3, PUR9_SYMTH
Q3A2D6, PUR9_SYNC1Q31R91, PUR9_SYNE7A5GIF4, PUR9_SYNPW
Q0IDE8, PUR9_SYNS3Q3B083, PUR9_SYNS9Q3AN13, PUR9_SYNSC
Q0AW31, PUR9_SYNWWP74741, PUR9_SYNY3Q9X0X6, PUR9_THEMA
B0KBQ1, PUR9_THEP3B0K3Q8, PUR9_THEPXQ8DIN5, PUR9_THEVB
B5YLE5, PUR9_THEYDC4LA41, PUR9_TOLATQ116T4, PUR9_TRIEI
B3E7F6, PUR9_TRIL1Q3M6G3, PUR9_TRIV2C5CL84, PUR9_VARPS
B7VM57, PUR9_VIBA3A7MXG0, PUR9_VIBC1A5F3U8, PUR9_VIBC3
Q9KV80, PUR9_VIBCHC3LQN2, PUR9_VIBCMQ87KT0, PUR9_VIBPA
Q8DD06, PUR9_VIBVUQ7MGT5, PUR9_VIBVYQ8D244, PUR9_WIGBR
Q8PQ19, PUR9_XANACQ4UZD2, PUR9_XANC8B0RN27, PUR9_XANCB
Q8PD47, PUR9_XANCPQ3BY85, PUR9_XANE5Q2P866, PUR9_XANOM
B2SRB2, PUR9_XANOPQ5H5H7, PUR9_XANORB2I4L7, PUR9_XYLF2
Q9PC10, PUR9_XYLFAB0U7A0, PUR9_XYLFMQ87D58, PUR9_XYLFT
A1JIJ7, PUR9_YERE8A7FNG6, PUR9_YERP3Q1C1V9, PUR9_YERPA
B2K130, PUR9_YERPBQ8ZAR3, PUR9_YERPEA9R8E1, PUR9_YERPG
Q1CN60, PUR9_YERPNA4TS14, PUR9_YERPPQ66FN5, PUR9_YERPS
B1JJL6, PUR9_YERPY

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.2.-
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