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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.
ENZYME entry: EC 2.1.3.11
| Accepted Name |
|---|
| N-succinylornithine carbamoyltransferase.
|
| Alternative Name(s) |
|---|
| N-succinyl-L-ornithine transcarbamylase. |
| SOTCase. |
| Succinylornithine transcarbamylase. |
| Reaction catalysed |
|---|
| Carbamoyl phosphate + N(2)-succinyl-L-ornithine <=> phosphate + N-succinyl-L-citrulline |
| Comment(s) |
|---|
- Specific for N-succinyl-L-ornithine and cannot use either L-ornithine
(see EC 2.1.3.3) or N-acetyl-L-ornithine (see EC 2.1.3.9) as
substrate.
- However, a single amino-acid substitution (Pro90Glu) is sufficient to
switch the enzyme to one that uses N-acetyl-L-ornithine as substrate.
- It is essential for de novo arginine biosynthesis in the obligate
anaerobe Bacteroides fragilis, suggesting that this organism uses an
alternative pathway for synthesizing arginine.
|
| Cross-references |
|---|
| BRENDA | 2.1.3.11 |
| EC2PDB | 2.1.3.11 |
| ExplorEnz | 2.1.3.11 |
| PRIAM enzyme-specific profiles | 2.1.3.11 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.1.3.11 |
| IUBMB Enzyme Nomenclature | 2.1.3.11 |
| IntEnz | 2.1.3.11 |
| MEDLINE | Find literature relating to 2.1.3.11 |
| MetaCyc | 2.1.3.11 |
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.1.3.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.1.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-