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ENZYME

ENZYME entry: EC 2.2.1.1

Accepted Name
transketolase
Alternative Name(s)
glycoaldehyde transferase
Reaction catalysed
D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate <=> aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate
Comment(s)
  • Wide specificity for both reactants, e.g. converts hydroxypyruvate and R-CHO into CO2 and R-CHOH-CO-CH2OH.
  • The enzyme from the bacterium Alcaligenes faecalis shows high activity with D-erythrose 4-phosphate as acceptor.
Cross-references
BRENDA2.2.1.1
EC2PDB2.2.1.1
ExplorEnz2.2.1.1
PRIAM enzyme-specific profiles2.2.1.1
KEGG Ligand Database for Enzyme Nomenclature2.2.1.1
IUBMB Enzyme Nomenclature2.2.1.1
IntEnz2.2.1.1
MEDLINEFind literature relating to 2.2.1.1
MetaCyc2.2.1.1
Rhea expert-curated reactions2.2.1.1
UniProtKB/Swiss-Prot
Q5E7R1, TKT1_ALIF1O94039, TKT1_CANAXP27302, TKT1_ECOLI
Q12630, TKT1_KLULAP57927, TKT1_PASMUQ9KUP2, TKT1_VIBCH
Q87LK8, TKT1_VIBPAQ8DCA2, TKT1_VIBVUQ7MHK7, TKT1_VIBVY
P51010, TKT1_XANFLP23254, TKT1_YEASTQ5DZP0, TKT2_ALIF1
P33570, TKT2_ECOLIP57958, TKT2_PASMUQ9KLW7, TKT2_VIBCH
Q87GY4, TKT2_VIBPAQ8D6H8, TKT2_VIBVUQ7MDD4, TKT2_VIBVY
Q60103, TKT2_XANFLP33315, TKT2_YEASTQ42677, TKT7_CRAPL
Q42675, TKTA_CRAPLQ8RWV0, TKTC1_ARATHF4IW47, TKTC2_ARATH
Q42676, TKTC_CRAPLP21725, TKTC_CUPNHQ7SIC9, TKTC_MAIZE
Q58092, TKTC_METJAQ43848, TKTC_SOLTUO20250, TKTC_SPIOL
Q2NL26, TKTL1_BOVINP51854, TKTL1_HUMANQ4R6M8, TKTL1_MACFA
Q99MX0, TKTL1_MOUSEQ2NKZ4, TKTL2_BOVINQ9H0I9, TKTL2_HUMAN
Q9D4D4, TKTL2_MOUSEQ58094, TKTN_METJAP21726, TKTP_CUPNH
O67642, TKT_AQUAEP45694, TKT_BACSUQ6B855, TKT_BOVIN
P57195, TKT_BUCAIQ8KA26, TKT_BUCAPQ89AY2, TKT_BUCBP
P29277, TKT_CERSPQ556J0, TKT_DICDIA0A0I9QGZ2, TKT_GEOSE
P43757, TKT_HAEINQ9KAD7, TKT_HALH5P29401, TKT_HUMAN
Q60HC7, TKT_MACFAP40142, TKT_MOUSEP59956, TKT_MYCBO
P47312, TKT_MYCGEP46708, TKT_MYCLEP75611, TKT_MYCPN
P9WG24, TKT_MYCTOP9WG25, TKT_MYCTUQ8YRU9, TKT_NOSS1
Q5R1W6, TKT_PANTRA6YB01, TKT_PHYPOP34736, TKT_PICST
Q5R4C1, TKT_PONABP84540, TKT_POPEUP50137, TKT_RAT
P58333, TKT_RHIMEP0CZ16, TKT_RHOCAD5AV94, TKT_RHOCB
Q9URM2, TKT_SCHPOP56900, TKT_SINMWQ5HG77, TKT_STAAC
P66962, TKT_STAAMP99161, TKT_STAANQ6GH64, TKT_STAAR
Q6G9L6, TKT_STAASP66963, TKT_STAAWQ5HPJ9, TKT_STAEQ
Q8CPC7, TKT_STAESQ5XAK5, TKT_STRP6Q8NZX4, TKT_STRP8
P22976, TKT_STRPNO83571, TKT_TREPA

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.2.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.2.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-