ENZYME entry: EC 2.2.1.5
Accepted Name |
2-hydroxy-3-oxoadipate synthase.
|
Alternative Name(s) |
2-hydroxy-3-oxoadipate glyoxylate-lyase (carboxylating). |
2-hydroxy-3-oxoadipate synthetase. |
alpha-ketoglutaric-glyoxylic carboligase. |
oxoglutarate: glyoxylate carboligase. |
Reaction catalysed |
2-oxoglutarate + glyoxylate + H(+) <=> 2-hydroxy-3-oxoadipate + CO2 |
Comment(s) |
- The product decarboxylates to 5-hydroxy-4-oxopentanoate.
- The enzyme can decarboxylate 2-oxoglutarate.
- Acetaldehyde can replace glyoxylate.
- Formerly EC 4.1.3.15.
|
Cross-references |
BRENDA | 2.2.1.5 |
EC2PDB | 2.2.1.5 |
ExplorEnz | 2.2.1.5 |
PRIAM enzyme-specific profiles | 2.2.1.5 |
KEGG Ligand Database for Enzyme Nomenclature | 2.2.1.5 |
IUBMB Enzyme Nomenclature | 2.2.1.5 |
IntEnz | 2.2.1.5 |
MEDLINE | Find literature relating to 2.2.1.5 |
MetaCyc | 2.2.1.5 |
Rhea expert-curated reactions | 2.2.1.5 |
UniProtKB/Swiss-Prot |
Q7U0A6, KGD_MYCBO; | A1KI36, KGD_MYCBP; | Q9CC97, KGD_MYCLE; |
Q73WX4, KGD_MYCPA; | A0R2B1, KGD_MYCS2; | A3Q3N5, KGD_MYCSJ; |
A1UK81, KGD_MYCSK; | Q1B4V6, KGD_MYCSS; | A5U1U6, KGD_MYCTA; |
P9WIS4, KGD_MYCTO; | P9WIS5, KGD_MYCTU; | A0PVU7, KGD_MYCUA; |
A1TDK2, KGD_MYCVP; |
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ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.2.1.-
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