ENZYME entry: EC 2.3.1.135
Accepted Name |
Phosphatidylcholine--retinol O-acyltransferase.
|
Alternative Name(s) |
Lecithin retinol acyl transferase. |
Lecithin--retinol acyltransferase. |
Lecithin-retinol acyltransferase. |
Retinyl ester synthase. |
Reaction catalysed |
Phosphatidylcholine + retinol--[cellular-retinol-binding-protein] <=> 2-acylglycerophosphocholine + retinyl-ester--[cellular-retinol-binding-protein] |
Comment(s) |
- A key enzyme in retinoid metabolism, catalyzing the transfer of an
acyl group from the sn-1 position of phosphatidylcholine to retinol,
forming retinyl esters which are then stored.
- Recognizes the substrate both in free form and when bound to
cellular-retinol-binding-protein, but has higher affinity for the
bound form.
- Can also esterify 11-cis-retinol.
|
Cross-references |
BRENDA | 2.3.1.135 |
EC2PDB | 2.3.1.135 |
ExplorEnz | 2.3.1.135 |
PRIAM enzyme-specific profiles | 2.3.1.135 |
KEGG Ligand Database for Enzyme Nomenclature | 2.3.1.135 |
IUBMB Enzyme Nomenclature | 2.3.1.135 |
IntEnz | 2.3.1.135 |
MEDLINE | Find literature relating to 2.3.1.135 |
MetaCyc | 2.3.1.135 |
UniProtKB/Swiss-Prot |
|
View entry in original ENZYME format
View entry in raw text format (no links)
All
ENZYME /
UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-