ENZYME entry: EC 2.3.1.149

PURL: https://purl.expasy.org/enzyme/EC/2.3.1.149

Accepted Name

platelet-activating factor acetyltransferase

Alternative Name(s)

PAF acetyltransferase

Reaction catalysed

a 1-organyl-2-lyso-sn-glycero-3-phospholipid + a 1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine = a 1-organyl-2-acetyl-sn-glycero-3-phospholipid + a 1-O-alkyl-sn-glycero-3-phosphocholine

Comment(s)

Catalyzes the transfer of the acetyl group from 1-alkyl-2-acyl- sn-glycero-3-phosphocholine (platelet-activating factor) to the sn-2 position of lyso-glycerophospholipids containing ethanolamine, choline, serine, inositol or phosphate groups at the sn-3 position as well as to sphingosine and long-chain fatty alcohols.
The organyl group can be alkyl, acyl or alk-1-enyl (sometimes also collectively referred to as 'radyl').

Cross-references

BRENDA

2.3.1.149

EC2PDB

2.3.1.149

ExplorEnz

2.3.1.149

KEGG Ligand Database for Enzyme Nomenclature

2.3.1.149

IUBMB Enzyme Nomenclature

2.3.1.149

MEDLINE

Find literature relating to 2.3.1.149

MetaCyc

2.3.1.149

Rhea expert-curated reactions

2.3.1.149

UniProtKB/Swiss-Prot

P79106, PAFA2_BOVIN	Q99487, PAFA2_HUMAN	Q8VDG7, PAFA2_MOUSE
P83006, PAFA2_RAT

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All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.

All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-