ENZYME entry: EC 2.3.1.149
| Accepted Name |
|---|
| Platelet-activating factor acetyltransferase.
|
| Alternative Name(s) |
|---|
| PAF acetyltransferase. |
| Reaction catalysed |
|---|
| 1-alkyl-2-acetyl-sn-glycero-3-phosphocholine + 1-organyl-2-lyso-sn-glycero-3-phospholipid <=> 1-organyl-2-lyso-sn-glycero-3-phosphocholine + 1-alkyl-2-acetyl-sn-glycero-3-phospholipid |
| Comment(s) |
|---|
- Catalyzes the transfer of the acetyl group from 1-alkyl-2-acyl-
sn-glycero-3-phosphocholine (platelet-activating factor) to the sn-2
position of lyso-glycerophospholipids containing ethanolamine,
choline, serine, inositol or phosphate groups at the sn-3 position as
well as to sphingosine and long-chain fatty alcohols.
- The organyl group can be alkyl, acyl or alk-1-enyl (sometimes also
collectively referred to as 'radyl').
|
| Cross-references |
|---|
| BRENDA | 2.3.1.149 |
| EC2PDB | 2.3.1.149 |
| ExplorEnz | 2.3.1.149 |
| PRIAM enzyme-specific profiles | 2.3.1.149 |
| KEGG Ligand Database for Enzyme Nomenclature | 2.3.1.149 |
| IUBMB Enzyme Nomenclature | 2.3.1.149 |
| IntEnz | 2.3.1.149 |
| MEDLINE | Find literature relating to 2.3.1.149 |
| MetaCyc | 2.3.1.149 |
| UniProtKB/Swiss-Prot |
|
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