ID   2.3.1.16
DE   acetyl-CoA C-acyltransferase.
AN   3-ketoacyl-CoA thiolase.
AN   beta-ketothiolase.
CA   acetyl-CoA + an acyl-CoA = a 3-oxoacyl-CoA + CoA.
CC   -!- The enzyme, found in both eukaryotes and in prokaryotes, is involved
CC       in degradation pathways such as fatty acid beta-oxidation.
CC   -!- The enzyme acts on 3-oxoacyl-CoAs to produce acetyl-CoA and an acyl-
CC       CoA shortened by two carbon atoms.
CC   -!- The reaction starts with the acylation of a nucleophilic cysteine at
CC       the active site by a 3-oxoacyl-CoA, with the concomitant release of
CC       acetyl-CoA.
CC   -!- In the second step the acyl group is transferred to CoA.
CC   -!- Most enzymes have a broad substrate range for the 3-oxoacyl-CoA. cf.
CC       EC 2.3.1.9.
DR   Q0KBP1, BKTB_CUPNH ;  O46629, ECHB_BOVIN ;  P55084, ECHB_HUMAN ;
DR   Q8HXX4, ECHB_MACFA ;  Q99JY0, ECHB_MOUSE ;  Q5R1W7, ECHB_PANTR ;
DR   Q60587, ECHB_RAT   ;  P34255, ECHH_CAEEL ;  I6XHI4, FADA5_MYCTU;
DR   I6XHJ3, FADA6_MYCTU;  Q6FF69, FADA_ACIAD ;  B7H1I1, FADA_ACIB3 ;
DR   B7I3P0, FADA_ACIB5 ;  B2I2J8, FADA_ACIBC ;  B0VLX5, FADA_ACIBS ;
DR   A3M1H9, FADA_ACIBT ;  B0VE46, FADA_ACIBY ;  A0KEL0, FADA_AERHH ;
DR   A4STF3, FADA_AERS4 ;  Q0VNZ7, FADA_ALCBS ;  Q5E8X7, FADA_ALIF1 ;
DR   B5FEW7, FADA_ALIFM ;  B6EGU1, FADA_ALISL ;  O32177, FADA_BACSU ;
DR   Q1QUW9, FADA_CHRSD ;  A8ACZ3, FADA_CITK8 ;  Q489W4, FADA_COLP3 ;
DR   A7MQM5, FADA_CROS8 ;  A7ZU50, FADA_ECO24 ;  Q8X8J4, FADA_ECO57 ;
DR   A8A6V0, FADA_ECOHS ;  A1AI32, FADA_ECOK1 ;  Q0TAL1, FADA_ECOL5 ;
DR   Q8FBI3, FADA_ECOL6 ;  P21151, FADA_ECOLI ;  Q1R467, FADA_ECOUT ;
DR   A4WFX5, FADA_ENT38 ;  Q9F0Y6, FADA_ENTCL ;  B2VFE0, FADA_ERWT9 ;
DR   B7LTZ0, FADA_ESCF3 ;  Q2SD23, FADA_HAHCH ;  Q5QXH8, FADA_IDILO ;
DR   A6TGM3, FADA_KLEP7 ;  A6VVM8, FADA_MARMS ;  A1TZR8, FADA_MARN8 ;
DR   Q6DAP6, FADA_PECAS ;  C6DI66, FADA_PECCP ;  Q7MZ91, FADA_PHOLL ;
DR   Q6LW07, FADA_PHOPR ;  Q48GW4, FADA_PSE14 ;  Q15ZF4, FADA_PSEA6 ;
DR   A6V383, FADA_PSEA7 ;  Q02PH7, FADA_PSEAB ;  Q9HZJ3, FADA_PSEAE ;
DR   Q1I7D5, FADA_PSEE4 ;  Q4KFC3, FADA_PSEF5 ;  P28790, FADA_PSEFR ;
DR   A4XSM9, FADA_PSEMY ;  Q93Q11, FADA_PSEOL ;  A5W6G9, FADA_PSEP1 ;
DR   Q3K9D9, FADA_PSEPF ;  Q88L01, FADA_PSEPK ;  Q9R9W0, FADA_PSEPU ;
DR   Q87ZB3, FADA_PSESM ;  Q3IJ24, FADA_PSET1 ;  Q4ZRA1, FADA_PSEU2 ;
DR   Q4FQC7, FADA_PSYA2 ;  Q1Q8K0, FADA_PSYCK ;  A5WH98, FADA_PSYWF ;
DR   Q21KB1, FADA_SACD2 ;  Q57HM7, FADA_SALCH ;  Q5PKQ3, FADA_SALPA ;
DR   P0A2H8, FADA_SALTI ;  P0A2H7, FADA_SALTY ;  A8G8D0, FADA_SERP5 ;
DR   A1S1I7, FADA_SHEAM ;  A3CYJ3, FADA_SHEB5 ;  A6WH99, FADA_SHEB8 ;
DR   Q12TB5, FADA_SHEDO ;  Q08A40, FADA_SHEFN ;  A3Q8U3, FADA_SHELP ;
DR   Q8EKS0, FADA_SHEON ;  A4Y1B5, FADA_SHEPC ;  A0KR49, FADA_SHESA ;
DR   Q0HPB8, FADA_SHESM ;  Q0I0T4, FADA_SHESR ;  A1RDW3, FADA_SHESW ;
DR   Q31UE3, FADA_SHIBS ;  Q32A20, FADA_SHIDS ;  Q0SZ35, FADA_SHIF8 ;
DR   Q83PG2, FADA_SHIFL ;  Q3YVC2, FADA_SHISS ;  A4VKA4, FADA_STUS1 ;
DR   A5F464, FADA_VIBC3 ;  Q9KNI0, FADA_VIBCH ;  Q87TP0, FADA_VIBPA ;
DR   Q8DDK5, FADA_VIBVU ;  Q7MQI0, FADA_VIBVY ;  A1JIG3, FADA_YERE8 ;
DR   A7FDF1, FADA_YERP3 ;  Q1C2C3, FADA_YERPA ;  Q8ZAM9, FADA_YERPE ;
DR   Q1CNA0, FADA_YERPN ;  A4TR28, FADA_YERPP ;  Q66FR9, FADA_YERPS ;
DR   A0KK76, FADI_AERHH ;  A4SMT9, FADI_AERS4 ;  Q5E3U0, FADI_ALIF1 ;
DR   B5FGB5, FADI_ALIFM ;  B4RTU9, FADI_ALTMD ;  A8ADP1, FADI_CITK8 ;
DR   Q47ZB6, FADI_COLP3 ;  A7MH80, FADI_CROS8 ;  A7ZPF9, FADI_ECO24 ;
DR   B7UFZ9, FADI_ECO27 ;  B7MGV8, FADI_ECO45 ;  B7LBJ6, FADI_ECO55 ;
DR   Q8XCN9, FADI_ECO57 ;  B5YXY5, FADI_ECO5E ;  B7NP25, FADI_ECO7I ;
DR   B7MY17, FADI_ECO81 ;  B7M6M3, FADI_ECO8A ;  C4ZVN3, FADI_ECOBW ;
DR   B1X9L5, FADI_ECODH ;  A8A2L1, FADI_ECOHS ;  A1ADI9, FADI_ECOK1 ;
DR   Q0TFA5, FADI_ECOL5 ;  Q8FFG3, FADI_ECOL6 ;  B1IXA4, FADI_ECOLC ;
DR   P76503, FADI_ECOLI ;  B7N5V3, FADI_ECOLU ;  B6I6Q5, FADI_ECOSE ;
DR   B1LME8, FADI_ECOSM ;  Q1R971, FADI_ECOUT ;  A4WCW7, FADI_ENT38 ;
DR   B2VJ10, FADI_ERWT9 ;  B7LLC9, FADI_ESCF3 ;  Q5QXN5, FADI_IDILO ;
DR   B5XVW1, FADI_KLEP3 ;  A6TC20, FADI_KLEP7 ;  Q6D2L6, FADI_PECAS ;
DR   C6DAL8, FADI_PECCP ;  Q7N287, FADI_PHOLL ;  Q6LTK4, FADI_PHOPR ;
DR   Q15VA3, FADI_PSEA6 ;  Q3IEE3, FADI_PSET1 ;  B5EZS0, FADI_SALA4 ;
DR   A9MJ36, FADI_SALAR ;  Q57LW5, FADI_SALCH ;  B5FPN2, FADI_SALDC ;
DR   B5R3S0, FADI_SALEP ;  B4TCA9, FADI_SALHS ;  B4SZR1, FADI_SALNS ;
DR   Q5PCX7, FADI_SALPA ;  A9N452, FADI_SALPB ;  C0PZX5, FADI_SALPC ;
DR   B5BBA0, FADI_SALPK ;  B4TQC3, FADI_SALSV ;  Q8Z4Y9, FADI_SALTI ;
DR   Q8ZNA6, FADI_SALTY ;  A8GH87, FADI_SERP5 ;  A1S7L7, FADI_SHEAM ;
DR   B8EE97, FADI_SHEB2 ;  A3D685, FADI_SHEB5 ;  A6WQ26, FADI_SHEB8 ;
DR   A9KTW7, FADI_SHEB9 ;  Q12P12, FADI_SHEDO ;  Q07ZP7, FADI_SHEFN ;
DR   B0TL22, FADI_SHEHH ;  A3QFP4, FADI_SHELP ;  Q8ECP6, FADI_SHEON ;
DR   A8H5T2, FADI_SHEPA ;  A4Y898, FADI_SHEPC ;  B8CPY7, FADI_SHEPW ;
DR   A0KV75, FADI_SHESA ;  A8FTR6, FADI_SHESH ;  Q0HKD2, FADI_SHESM ;
DR   Q0HWN4, FADI_SHESR ;  A1RI91, FADI_SHESW ;  B1KKT1, FADI_SHEWM ;
DR   B2TWV5, FADI_SHIB3 ;  Q31YB6, FADI_SHIBS ;  Q32DJ3, FADI_SHIDS ;
DR   Q0T2E5, FADI_SHIF8 ;  Q83K95, FADI_SHIFL ;  Q3YZM1, FADI_SHISS ;
DR   A5F2P1, FADI_VIBC3 ;  Q9KT59, FADI_VIBCH ;  Q87MM2, FADI_VIBPA ;
DR   Q8DB48, FADI_VIBVU ;  Q7MIS4, FADI_VIBVY ;  A1JK23, FADI_YERE8 ;
DR   A7FGK0, FADI_YERP3 ;  Q1C659, FADI_YERPA ;  B2K8J6, FADI_YERPB ;
DR   Q8ZD46, FADI_YERPE ;  A9R7W9, FADI_YERPG ;  Q1CHK1, FADI_YERPN ;
DR   A4TM83, FADI_YERPP ;  Q668V0, FADI_YERPS ;  B1JGG1, FADI_YERPY ;
DR   C8YNG6, KAT1_PETHY ;  P07857, SCP2_BOVIN ;  Q07598, SCP2_CHICK ;
DR   P22307, SCP2_HUMAN ;  P32020, SCP2_MOUSE ;  O62742, SCP2_RABIT ;
DR   P11915, SCP2_RAT   ;  Q8LF48, THIK1_ARATH;  Q56WD9, THIK2_ARATH;
DR   Q570C8, THIK5_ARATH;  P33290, THIKA_CANTR;  Q921H8, THIKA_MOUSE;
DR   P21775, THIKA_RAT  ;  P33291, THIKB_CANTR;  Q8VCH0, THIKB_MOUSE;
DR   P07871, THIKB_RAT  ;  Q8SVA6, THIK_ENCCU ;  P09110, THIK_HUMAN ;
DR   Q05493, THIK_YARLI ;  P27796, THIK_YEAST ;  Q3T0R7, THIM_BOVIN ;
DR   P42765, THIM_HUMAN ;  Q8BWT1, THIM_MOUSE ;  Q5RES5, THIM_PONAB ;
DR   P13437, THIM_RAT   ;
//