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A new class EC 7, Translocases, has been added to the EC list. It will be part of ENZYME from release 2018_10. Read more about EC 7 here.

ENZYME entry: EC

Accepted Name
Isopenicillin-N N-acyltransferase.
Alternative Name(s)
Acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase.
Acyl-coenzyme A:isopenicillin N acyltransferase.
Isopenicillin N:acyl-CoA acyltransferase.
Reaction catalysed
Phenylacetyl-CoA + isopenicillin N + H(2)O <=> CoA + penicillin G + L-2-aminohexanedioate
  • Proceeds by a two stage mechanism via 6-aminopenicillanic acid.
  • Different from EC
PRIAM enzyme-specific profiles2.3.1.164
KEGG Ligand Database for Enzyme Nomenclature2.3.1.164
IUBMB Enzyme Nomenclature2.3.1.164
MEDLINEFind literature relating to
P21133, AAAA_EMENI;  P15802, AAAA_PENCH;  

View entry in original ENZYME format
View entry in raw text format (no links)
All UniProtKB/Swiss-Prot entries referenced in this entry, with possibility to download in different formats, align etc.
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-