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ENZYME

ENZYME entry: EC 2.3.1.185

PURL: https://purl.expasy.org/enzyme/EC/2.3.1.185
Accepted Name
tropine acyltransferase
Alternative Name(s)
TAT
tropine acetyltransferase
tropine tigloyltransferase
Reaction catalysed
tropine + an acyl-CoA = an O-acyltropine + CoA + H(+)
Comment(s)
  • Exhibits absolute specificity for the endo/3alpha configuration found in tropine as pseudotropine (tropan-3beta-ol; see EC 2.3.1.186) is not a substrate.
  • Acts on a wide range of aliphatic acyl-CoA derivatives, with tigloyl- CoA and acetyl-CoA being the best substrates.
  • It is probably involved in the formation of the tropane alkaloid littorine, which is a precursor of hyoscyamine.
Cross-references
BRENDA2.3.1.185
EC2PDB2.3.1.185
ExplorEnz2.3.1.185
KEGG Ligand Database for Enzyme Nomenclature2.3.1.185
IUBMB Enzyme Nomenclature2.3.1.185
MEDLINEFind literature relating to 2.3.1.185
MetaCyc2.3.1.185
Rhea expert-curated reactions2.3.1.185

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-