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ENZYME

ENZYME entry: EC 2.3.1.191

Accepted Name
UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase
Alternative Name(s)
UDP-3-O-[3-hydroxymyristoyl]-D-glucosamine N-acyltransferase
UDP-3-O-acyl-glucosamine N-acyltransferase
Reaction catalysed
a UDP-3-O-[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + a (3R)-hydroxyacyl-[ACP] = a UDP-2-N,3-O-bis[(3R)-3-hydroxyacyl]-alpha-D-glucosamine + holo-[ACP] + H(+)
Comment(s)
  • The enzyme catalyzes a step of lipid A biosynthesis.
  • LpxD from Escherichia coli prefers (3R)-3-hydroxytetradecanoyl-[acyl- carrier protein], but it does not an absolute specificity for 14-carbon hydroxy fatty acids, as it can transfer other fatty acids, including odd-chain fatty acids, if they are available to the organism.
  • Formerly EC 2.3.1.n1.
Cross-references
BRENDA2.3.1.191
EC2PDB2.3.1.191
ExplorEnz2.3.1.191
KEGG Ligand Database for Enzyme Nomenclature2.3.1.191
IUBMB Enzyme Nomenclature2.3.1.191
MEDLINEFind literature relating to 2.3.1.191
MetaCyc2.3.1.191
Rhea expert-curated reactions2.3.1.191
UniProtKB/Swiss-Prot
F4JGP6, LPXD1_ARATHQ14JF8, LPXD1_FRAT1Q2A5L0, LPXD1_FRATH
Q0BNW4, LPXD1_FRATOQ5NI06, LPXD1_FRATTQ7NJG8, LPXD1_GLOVI
Q1IQB4, LPXD1_KORVEQ5X8X9, LPXD1_LEGPAQ5ZZB1, LPXD1_LEGPH
Q5X0C0, LPXD1_LEGPLQ3SRI1, LPXD1_NITWNQ215E0, LPXD1_RHOPB
Q30RG5, LPXD1_SULDNQ14G52, LPXD2_FRAT1Q2A4P6, LPXD2_FRATH
Q0BN22, LPXD2_FRATOQ5NEP9, LPXD2_FRATTQ7NJ21, LPXD2_GLOVI
Q1IP54, LPXD2_KORVEQ5X0T1, LPXD2_LEGPAQ5ZRD8, LPXD2_LEGPH
Q5WSK5, LPXD2_LEGPLQ3SMZ4, LPXD2_NITWNQ215C1, LPXD2_RHOPB
Q30RG4, LPXD2_SULDNQ7NH24, LPXD3_GLOVIQ6FCG5, LPXD_ACIAD
B7H1U9, LPXD_ACIB3B7I9U5, LPXD_ACIB5B2I321, LPXD_ACIBC
B0VMV2, LPXD_ACIBSA3M650, LPXD_ACIBTB0V6F7, LPXD_ACIBY
B9MGM7, LPXD_ACIETA1W908, LPXD_ACISJA0KHH3, LPXD_AERHH
Q8UFL5, LPXD_AGRFCQ21WY0, LPXD_ALBFTQ0VQE7, LPXD_ALCBS
Q5E3E9, LPXD_ALIF1Q0A526, LPXD_ALKEHB3ER76, LPXD_AMOA5
B8JFW7, LPXD_ANAD2Q2IPX9, LPXD_ANADEA7H9D4, LPXD_ANADF
B4UGV0, LPXD_ANASKO66817, LPXD_AQUAEQ5NZG5, LPXD_AROAE
A8I485, LPXD_AZOC5A1K6R1, LPXD_AZOSBQ5LH14, LPXD_BACFN
Q64XW8, LPXD_BACFRQ8A014, LPXD_BACTNQ8VQ23, LPXD_BARHE
Q6G1J4, LPXD_BARQUA9ISM1, LPXD_BART1Q7VRD6, LPXD_BLOFL
Q493C2, LPXD_BLOPBQ2L151, LPXD_BORA1Q7WJ84, LPXD_BORBR
Q7WA50, LPXD_BORPAA9INS9, LPXD_BORPDQ7VYC0, LPXD_BORPE
Q89KQ2, LPXD_BRADUA5EK46, LPXD_BRASBA4YVF7, LPXD_BRASO
B2S603, LPXD_BRUA1Q2YRQ3, LPXD_BRUA2P0C111, LPXD_BRUAB
A9M5G6, LPXD_BRUC2C0RJC2, LPXD_BRUMBP0A3P4, LPXD_BRUME
A5VQS5, LPXD_BRUO2B0CGV1, LPXD_BRUSIP0A3P5, LPXD_BRUSU
B1YS64, LPXD_BURA4A0K8D3, LPXD_BURCHB4ECM1, LPXD_BURCJ
Q0BE25, LPXD_BURCMQ39F53, LPXD_BURL3A9AIM4, LPXD_BURM1
A3MKT2, LPXD_BURM7A2SB83, LPXD_BURM9Q62JD4, LPXD_BURMA
A1V558, LPXD_BURMSB1JUE0, LPXD_BURO0Q1BHH2, LPXD_BURO1
A3NWM0, LPXD_BURP0Q3JR39, LPXD_BURP1A3NAT7, LPXD_BURP6
Q63T22, LPXD_BURPSQ2SWY8, LPXD_BURTAA4JF65, LPXD_BURVG
A7ZD79, LPXD_CAMC1A7GYD3, LPXD_CAMC5A7H3V3, LPXD_CAMJD
Q9PHU0, LPXD_CAMJEQ5HVJ4, LPXD_CAMJRB9KGF3, LPXD_CAMLR
B0SZ11, LPXD_CAUSKQ9A713, LPXD_CAUVCB8GWR3, LPXD_CAUVN
B3PBQ8, LPXD_CELJUQ11IJ0, LPXD_CHESBQ5L612, LPXD_CHLAB
Q3ARF9, LPXD_CHLCHQ823E0, LPXD_CHLCVQ254I9, LPXD_CHLFF
Q3B382, LPXD_CHLL3Q9PKF1, LPXD_CHLMUQ9Z8N6, LPXD_CHLPN
B0B7F9, LPXD_CHLT2Q3KMB9, LPXD_CHLTAB0BBM4, LPXD_CHLTB
Q8KCQ3, LPXD_CHLTEP0CD76, LPXD_CHLTRA0M2A1, LPXD_CHRFK
Q1R023, LPXD_CHRSDQ7NVY4, LPXD_CHRVOB5EEW8, LPXD_CITBB
Q485G0, LPXD_COLP3B6J8K9, LPXD_COXB1B6J168, LPXD_COXB2
A9KC34, LPXD_COXBNA9NC98, LPXD_COXBRQ83DT0, LPXD_COXBU
Q1LNE8, LPXD_CUPMCQ0KA26, LPXD_CUPNHQ470E7, LPXD_CUPPJ
B3R2A7, LPXD_CUPTRQ11WA1, LPXD_CYTH3Q47F82, LPXD_DECAR
A9BMM2, LPXD_DELASA8ZYC0, LPXD_DESOHQ6AJ06, LPXD_DESPS
P65323, LPXD_ECO57Q0TLF4, LPXD_ECOL5P65322, LPXD_ECOL6
P21645, LPXD_ECOLIQ1RG10, LPXD_ECOUTA4XWT1, LPXD_ECTM1
B2KAU6, LPXD_ELUMPA7NAP3, LPXD_FRATFQ8R6D9, LPXD_FUSNN
B9M8V8, LPXD_GEODFQ39T44, LPXD_GEOMGQ74AT5, LPXD_GEOSL
C6E5B9, LPXD_GEOSMB7KFG9, LPXD_GLOC7Q0BTL2, LPXD_GRABC
Q7VM24, LPXD_HAEDUQ4QLZ4, LPXD_HAEI8P43888, LPXD_HAEIN
Q2SBQ8, LPXD_HAHCHA1WT71, LPXD_HALHLQ7VH68, LPXD_HELHP
Q1CUW5, LPXD_HELPHQ9ZMN6, LPXD_HELPJO24991, LPXD_HELPY
A4G4T1, LPXD_HERARQ0I387, LPXD_HISS1Q31G52, LPXD_HYDCU
Q0C1B1, LPXD_HYPNAQ5R0Z4, LPXD_IDILOA6SZP1, LPXD_JANMA
Q1MPK2, LPXD_LAWIPB0SCK5, LPXD_LEPBAB0SKN3, LPXD_LEPBP
B1XXI5, LPXD_LEPCPQ65R81, LPXD_MANSMQ0APV5, LPXD_MARMM
A6VUT2, LPXD_MARMSB7KZG7, LPXD_METC4Q9AIP8, LPXD_METCA
A9W4H0, LPXD_METEPQ1H149, LPXD_METFKB3E0P9, LPXD_METI4
B8INJ6, LPXD_METNOB1ZLC2, LPXD_METPBB1LTP6, LPXD_METRJ
B0UQ03, LPXD_METS4B0JUA2, LPXD_MICANQ1D385, LPXD_MYXXD
Q5F5W6, LPXD_NEIG1B4RR13, LPXD_NEIG2A9M3S8, LPXD_NEIM0
Q9JX29, LPXD_NEIMAP95377, LPXD_NEIMBA1KRL2, LPXD_NEIMF
Q1QMM8, LPXD_NITHXQ3JEI7, LPXD_NITOCQ729I2, LPXD_NITV2
B8DSI1, LPXD_NITV9B2IUM5, LPXD_NOSP7Q8YSL0, LPXD_NOSS1
Q312H3, LPXD_OLEA2A1TN79, LPXD_PARC0A6LDS1, LPXD_PARD8
A1B1F2, LPXD_PARDPA7HY09, LPXD_PARL1Q2W4D3, LPXD_PARM1
Q7U841, LPXD_PARMWB2JIB6, LPXD_PARP8B2T5I4, LPXD_PARPJ
Q6MAE7, LPXD_PARUWQ13XC6, LPXD_PARXLQ9CJL0, LPXD_PASMU
Q6D8D3, LPXD_PECASB4RBY4, LPXD_PHEZHQ7N8N7, LPXD_PHOLL
Q6LN34, LPXD_PHOPRA6KWL3, LPXD_PHOV8A4SYU1, LPXD_POLAQ
A1VN50, LPXD_POLNAB1XTV3, LPXD_POLNSQ12A41, LPXD_POLSJ
B2RME3, LPXD_PORG3Q7MXT7, LPXD_PORGIA2BW42, LPXD_PROM5
Q31B90, LPXD_PROM9Q7VC79, LPXD_PROMAQ7V843, LPXD_PROMM
Q7V1R8, LPXD_PROMPQ46LE1, LPXD_PROMTQ48F69, LPXD_PSE14
Q15WF3, LPXD_PSEA6A6V1E2, LPXD_PSEA7B7V7U2, LPXD_PSEA8
Q02RB8, LPXD_PSEABQ9HXY6, LPXD_PSEAEQ1I636, LPXD_PSEE4
Q4KHG6, LPXD_PSEF5C3K605, LPXD_PSEFSA5W840, LPXD_PSEP1
Q3KHA2, LPXD_PSEPFB0KSA9, LPXD_PSEPGQ88MH0, LPXD_PSEPK
B1JBQ0, LPXD_PSEPWQ886N3, LPXD_PSESMQ3IIY4, LPXD_PSET1
Q4ZWR8, LPXD_PSEU2Q4FRI2, LPXD_PSYA2Q1QA19, LPXD_PSYCK
A1SYV3, LPXD_PSYINQ8XZI1, LPXD_RALN1B2UBB1, LPXD_RALPJ
Q2K8X9, LPXD_RHIECQ1MH46, LPXD_RHIJ3Q98MC4, LPXD_RHILO
Q92Q47, LPXD_RHIMEB9JEX8, LPXD_RHIR8Q7UEV1, LPXD_RHOBA
B6ISU1, LPXD_RHOCSQ2IW89, LPXD_RHOP2Q6N5Q9, LPXD_RHOPA
Q136B3, LPXD_RHOPSB3Q7J5, LPXD_RHOPTC3PM38, LPXD_RICAE
A8GLS2, LPXD_RICAHQ1RH94, LPXD_RICBRA8EX78, LPXD_RICCK
Q92JQ7, LPXD_RICCNQ4UNJ8, LPXD_RICFEA8F0C5, LPXD_RICM5
Q9ZED3, LPXD_RICPRC4K0C3, LPXD_RICPUP32202, LPXD_RICRI
B0BVR5, LPXD_RICROA8GQD0, LPXD_RICRSQ68XZ4, LPXD_RICTY
B7JUM7, LPXD_RIPO1Q5LS40, LPXD_RUEPOA1AWJ9, LPXD_RUTMC
Q21HI2, LPXD_SACD2Q57T29, LPXD_SALCHQ5PD75, LPXD_SALPA
P0A1X5, LPXD_SALTIP0A1X4, LPXD_SALTYQ12NX7, LPXD_SHEDO
Q085D2, LPXD_SHEFNQ8EGG5, LPXD_SHEONQ0HGW5, LPXD_SHESM
Q0HT72, LPXD_SHESRQ325W1, LPXD_SHIBSQ32JT0, LPXD_SHIDS
P65324, LPXD_SHIFLQ3Z5H9, LPXD_SHISSC3MBR0, LPXD_SINFN
A6U8L0, LPXD_SINMWQ2NRL7, LPXD_SODGMQ2LVL5, LPXD_SYNAS
Q3A555, LPXD_SYNC1Q31N90, LPXD_SYNE7A0LPR5, LPXD_SYNFM
Q2JVM2, LPXD_SYNJAQ2JLY8, LPXD_SYNJBQ5N5W9, LPXD_SYNP6
A5GKW4, LPXD_SYNPWQ3AYS2, LPXD_SYNS9Q3AIH3, LPXD_SYNSC
Q55612, LPXD_SYNY3Q8DMS9, LPXD_THEVBQ3SKN1, LPXD_THIDA
C4L854, LPXD_TOLATQ10VF5, LPXD_TRIEIQ3MEX5, LPXD_TRIV2
C5CKT0, LPXD_VARPSA1WHV2, LPXD_VEREIA5CWN8, LPXD_VESOH
Q9KPW2, LPXD_VIBCHQ87ME7, LPXD_VIBPAQ8DBF1, LPXD_VIBVU
Q7MIH0, LPXD_VIBVYQ8D2H2, LPXD_WIGBRQ7MAQ2, LPXD_WOLSU
Q8PML5, LPXD_XANACQ4USQ0, LPXD_XANC8Q8PAW3, LPXD_XANCP
Q3BVL4, LPXD_XANE5Q2P4B5, LPXD_XANOMQ5H1F0, LPXD_XANOR
B2I7P1, LPXD_XYLF2Q9PEI3, LPXD_XYLFAB0U239, LPXD_XYLFM
Q87EI2, LPXD_XYLFTP32203, LPXD_YERENQ1CAM4, LPXD_YERPA
P58611, LPXD_YERPEQ1CFF7, LPXD_YERPNQ667J9, LPXD_YERPS

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-