ID   2.3.1.217
DE   curcumin synthase.
CA   (E)-feruloyl-CoA + (E)-feruloylacetyl-CoA + H2O = CO2 + 2 CoA + curcumin.
CC   -!- A polyketide synthase from the plant Curcuma longa (turmeric).
CC   -!- Three isoforms exist, CURS1, CURS2 and CURS3.
CC   -!- While CURS1 and CURS2 prefer feruloyl-CoA as a starter substrate,
CC       CURS3 can accept 4-coumaroyl-CoA equally well (see EC 2.3.1.219).
DR   C0SVZ6, CURS1_CURLO;  C6L7V8, CURS2_CURLO;  C6L7V9, CURS3_CURLO;
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