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ENZYME

ENZYME entry: EC 2.3.1.221

PURL: https://purl.expasy.org/enzyme/EC/2.3.1.221
Accepted Name
noranthrone synthase
Alternative Name(s)
norsolorinic acid anthrone synthase
polyketide synthase A
Reaction catalysed
hexanoyl-[ACP] + 7 malonyl-CoA + 6 H(+) = noranthrone + holo-[ACP] + 7 CO2 + 7 CoA + 2 H2O
Comment(s)
  • A multi-domain polyketide synthase involved in the synthesis of aflatoxins in the fungus Aspergillus parasiticus.
  • The hexanoyl starter unit is provided to the acyl-carrier protein (ACP) domain by a dedicated fungal fatty acid synthase.
Cross-references
BRENDA2.3.1.221
EC2PDB2.3.1.221
ExplorEnz2.3.1.221
KEGG Ligand Database for Enzyme Nomenclature2.3.1.221
IUBMB Enzyme Nomenclature2.3.1.221
MEDLINEFind literature relating to 2.3.1.221
MetaCyc2.3.1.221
Rhea expert-curated reactions2.3.1.221
UniProtKB/Swiss-Prot
Q12053, AFLC_ASPPUQ30DW5, PKSA_DOTSEM2XHZ5, PKSA_DOTSN
Q12397, STCA_EMENI

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All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.1.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.3.-.-
All ENZYME / UniProtKB/Swiss-Prot entries corresponding to 2.-.-.-