ID 2.3.1.226 DE carboxymethylproline synthase. CA (S)-1-pyrroline-5-carboxylate + malonyl-CoA + H2O + H(+) = (2S,5S)-5- CA carboxymethylproline + CO2 + CoA. CC -!- The enzyme is involved in the biosynthesis of the carbapenem beta- CC lactam antibiotic (5R)-carbapen-2-em-3-carboxylate in the bacterium CC Pectobacterium carotovorum. DR Q9XB60, CARB_PECCC ; //