ID   2.3.1.231
DE   tRNA(Phe) {7-[3-amino-3-(methoxycarbonyl)propyl]wyosine(37)-N}-
DE   methoxycarbonyltransferase.
AN   tRNA-yW synthesizing enzyme-4.
CA   7-[(3S)-(3-amino-3-methoxycarbonyl)propyl]wyosine(37) in tRNA(Phe) +
CA   CO2 + S-adenosyl-L-methionine = 2 H(+) + S-adenosyl-L-homocysteine +
CA   wybutosine(37) in tRNA(Phe).
CC   -!- The enzyme is found only in eukaryotes, where it is involved in the
CC       biosynthesis of wybutosine, a hypermodified tricyclic base found at
CC       position 37 of certain tRNAs.
CC   -!- The modification is important for translational reading-frame
CC       maintenance.
CC   -!- In some species that produce hydroxywybutosine the enzyme uses
CC       7-[2-hydroxy-3-amino-3-(methoxycarbonyl)propyl]wyosine(37) in
CC       tRNA(Phe) as substrate.
CC   -!- The enzyme also has the activity of EC 2.1.1.290.
DR   Q4WVD1, TYW4_ASPFU ;  Q2U6D4, TYW4_ASPOR ;  Q5A931, TYW4_CANAL ;
DR   Q6FXA5, TYW4_CANGA ;  Q5BH52, TYW4_EMENI ;  Q75AW4, TYW4_EREGS ;
DR   Q4IER0, TYW4_GIBZE ;  O60294, TYW4_HUMAN ;  Q8BYR1, TYW4_MOUSE ;
DR   Q9P3K9, TYW4_NEUCR ;  Q5XIA3, TYW4_RAT   ;  O60157, TYW4_SCHPO ;
DR   Q6C3P4, TYW4_YARLI ;  Q08282, TYW4_YEAST ;
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