ID 2.3.1.235 DE tetracenomycin F2 synthase. CA 8 H(+) + 10 malonyl-CoA = 10 CO2 + 10 CoA + 2 H2O + tetracenomycin F2. CC -!- A multi-domain polyketide synthase involved in the synthesis of CC tetracenomycin in the bacterium Streptomyces glaucescens. CC -!- It involves a ketosynthase complex, an acyl carrier protein, CC a malonyl CoA:ACP acyltransferase, and a cyclase. CC -!- A malonyl-CoA molecule is initially bound to the acyl carrier protein CC and decarboxylated to form an acetyl starter unit. CC -!- Additional two-carbon units are added from nine more malonyl-CoA CC molecules. DR P16558, TCMJ_STRGA ; P16538, TCMK_STRGA ; P16539, TCML_STRGA ; DR P12884, TCMM_STRGA ; P16559, TCMN_STRGA ; //